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Alleles

Biology Allele frequencyAllele-specific PCR

Alleles
An allele, (US)) is one of a series of different forms of a gene.

 


alleles whose summed effect is that of lethality for example, four alleles each of which would be lethal 25% of the time (or to 25% of their bearers), are equivalent to one lethal allele.
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z ...

multiple alleles
one of three or more alternative forms of allelic series that all map to a specific locus
Source: Jenkins, John B. 1990. Human Genetics, 2nd Edition. New York: Harper & Row ...

Alleles: Alternative forms of a genetic characteristic.
Amino acids: Small molecules that form the building blocks of proteins.
Autosome: All chro mosomes except those involved in sex determination.

Alleles. Alternate forms of a gene or DNA sequence, which occur on either of two homologous chromosomes in a diploid organism. (See DNA polymorphism.) ...

Alleles
Alternative forms of a gene. For example, the mutants putA601 and putA736 each have a different mutation in the putA gene.

Alleles alternate forms for genes
(allelo = one another‚ parallel)
Allelopathy when plants secrete chemicals to retard/inhibit the growth of other plants
(allelo = one another‚ parallel; pathos = disease‚ suffering) ...

alleles Alternate forms of a gene.
allergens Antigens that provoke an allergic reaction.
alpha decay Type of radioactive decay in which a radioisotope emits a large but slow-moving particle consisting of two protons and two neutrons.

Alleles and Loci
An allele is a gene that has more than one form. Each of the forms is referred to as an allele. For example, the gene for red flowers and the gene for white flowers are two different alleles.

[edit] Alleles
The serotonin transporter gene (SLC6A4) with the 5-HTTLPR is located on chromosome 17.

Alleles in the suspect's DNA are different from alleles of a victim's DNA.

Alleles: Alternative forms of a genetic locus; a single allele for each locus is inherited separately from each parent (e.g., at a locus for eye color the allele might result in blue or brown eyes).
...

Alleles for a particular phenotype determine what characteristic an organism will express, as with the following example where ...

Alleles carrying particular DNA sequences associated with the presence of disease.
DNA (deoxyribonucleic acid) ...

Alleles can increase or decrease in frequency due to drift. The average expected change in allele frequency is zero, since increasing or decreasing in frequency is equally probable.

Both alleles encode a PKG, a protein kinase (an enzyme that attaches phosphate groups to target proteins) that is activated by the "second messenger" cyclic GMP (cGMP) [More].

multiple alleles A condition in which more than two alleles exist for a given trait.
multiple fission Asexual reproduction by the splitting of a cell or organism into many cells or organisms. See schizogony.

Codominant alleles occur when rather than expressing an intermediate phenotype, the heterozygotes express both homozygous phenotypes. An example is in human ABO blood types, the heterozygote AB type manufactures antibodies to both A and B types.

More than 250 alleles are associated with two genes called BRCA1 and BRCA2, which can cause a rare, inherited form of breast cancer. Is it appropriate to discriminate against every woman who bears a mutation in these genes?

Genotype The alleles present in an individual at the locus (loci) under consideration. Alternatively, the sum of all the alleles present in a genome.

The loss or gain of alleles from a population due to the emigration or immigration of fertile individuals, or the transfer of gametes, between populations.
gene pool
The total aggregate of genes in a population at any one time.

We inherit pairs of alleles from our parents for each trait. These alleles reside at a specific site on a chromosome called its locus (loci, plural). There are many genes at many loci on each of our chromosomes.

Dominant -- alleles that determine the phenotype displayed in a heterozygote with another (recessive) allele. Down syndrome -- a type of mental deficiency due to trisomy (three copies) of autosome 21, a translocation of 21 or mosaicism.

In other words the alleles that mark
>the genes of interest may occur more frequently or less frequently
>depending on the group one is analyzing. The text is quick to add that
>more research needs to be done in this field before we have a ...

Gene flow: the transfer of genes (actually, alleles) from one population to another.

Polygenic disorders Genetic disorders resulting from the combined action of alleles of more than one gene (e.g., heart disease, diabetes, and some cancers).

The three common apolipoprotein E (ApoE) alleles differentially contribute to the risk of Alzheimer's disease (AD).

The term proposed by Winkler (1930) for a process of interaction between alleles at meiosis. The term was re-introduced by Lindegren (1953) to account for aberrant ratios in the products of meiosis, apparently arising from such interaction.

from cis and trans, for the functional unit of the hereditary material defined by the phenotype of the trans (repulsion)heterokaryon or heterozygote for two recessive mutations: if this phenotype is mutant, the mutations are said to be alleles and to ...

Dominance: The property possessed by some alleles of determining the phenotype for any particular gene by masking the effects of the other allele (when heterozygous).

So a haplotype can refer to a combination of alleles in a single gene, or it could be alleles across multiple genes. It could be single nucleotide polymorphisms that are not in a gene but are in-between genes.

Each gene is comprised of two alleles, one inherited from the father and one from the mother. However, within a population, many alleles may exist for one gene. Hair colour in humans is a great example! See also genes.

Different alleles produce variation in inherited traits such as hair colour or blood type. In an individual, one form of the allele (the dominant one) may be expressed more than another form (the recessive one). [Talking Glossary] ...

allele - one variant of a particular gene; for example, there are blue and brown alleles of the eye-color gene.
anaphase - phase of mitosis where sister chromatids separate and daughter chromosomes migrate to opposite poles of the cell.

The situation in which a heterozygote shows the phenotypic effects of both alleles fully & equally, (eg blood group antigens).
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Genotype. The genetic makeup of an organism, with respect to a given genetic locus, the alleles it carries
Genus. (plural: genera) The level of the taxonomic hierarchy above the species but below the family level ...

classical mapping line Strains that are primarily used for classical genetic mapping. Individual plants are scored for visible traits and map locations are based upon recombination frequencies between visible alleles.

during anaphase 1 of meiosis, producing gametes containing only one allele of each gene. Such an occurrence is the physical mechanism underlying the first law of Mendelian genetics and is particularly important when the two separated alleles are ...

Used in detection of genetic disease alleles etc.
RT-PCRPCR amplification from an RNA template. The first step involves synthesis of a single strand of cDNA on the RNA template using reverse transcriptase.

See also: Allele, Gene, Organ, DNA, Chromosome