Antigenic determinant
From Wikipedia, the free encyclopedia
Jump to: navigation, search ...
Antigenic determinant
An epitope, also known as antigenic determinant, is the part of a macromolecule that is recognized by the immune system, specifically by antibodies, B cells, or T cells.
Antigenic determinant. A surface feature of a microorganism or macromolecule, such as a glycoprotein, that elicits an immune response.
antigenic determinant The site on an antigen to which an antibody binds, forming an antigen-antibody complex.
antigenic determinant Area on an antigen molecule that binds with antibody or specific receptor sites on the sensitized lymphocyte; it "determines" the specificity of the antibody or lymphocyte. See epitope.
An antigenic determinant, a site on the antigen that the immune system responds to by making antibody, can frequently be one unique structure on the antigen.
A unique antigenic determinant recognizes and binds to a site on the antigen, leading to the destruction of the antigen in several ways. The ends of the Y are the antigen-combining site that is different for each antigen.
Specific varieties of the virus are generally named according to the particular antigenic determinants of hemagglutinin (13 major types) and neuraminidase (9 major types) surface proteins they possess, as in influenza A(H2N1) and A(H3N2).
(Science: immunology) a thermodynamic expression of the strength of interaction between a single antigen binding Site and a single antigenic determinant (and thus of the stereochemical compatibility between them), ...
This site binds to a portion of the antigen called an antigenic determinant or epitope.
The binding, like that between an enzyme and its substrate depends on complementarity of the surface of the receptor and the surface of the epitope.
A single species of antibody able to react with only a single specified antigen or antigenic determinant.
A localized region on the surface of an antigen that is chemically recognized by antibodies; also called antigenic determinant.
equilibrium ...
Epitope: The specific site on an antigen that is recognized by an antibody (also known as the antigenic determinant).
But the yearly changes we see in the population when we need new vaccines every year are sort of secondary, minor changes, that happen in the antigenic determinants on these surface, glycoproteins. On the hemagglutinin and the neuraminidase.
 See also: Antigen, Antibody, Molecule, Antibodies, Protein
  
|
RSS
