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Antisense RNA

Biology AntisenseAntisense strand

Antisense RNA
Messenger RNA (mRNA) is single-stranded. Its sequence of nucleotides is called "sense" because it results in a gene product (protein).

 


Antisense RNA. A complementary RNA sequence that binds to a naturally occurring (sense) mRNA molecule, thus blocking its translation. (See RNA.)
Asexual reproduction. Nonsexual means of reproduction which can include grafting and budding.

Antisense RNA
An RNA molecule that can hybridize to an mRNA molecule. Hybridization of an antisense RNA molecule to the translation start sites on an mRNA prevents the initiation of translation.

Antisense RNA can be injected into eukaryotic cells as a control mechanism.
Types of control in Eukaryotes ...

Regulation of plasmids based on the ColE1 origin, a high copy number origin, require an antisense RNA. A gene close to the origin, RNAII is transcribed and the 3'-OH of the transcript primes the origin only if it is cleaved by RNase H.

There's a second aspect of antisense, which is a fairly new discovery, called antisense RNA.

Antisense rna (← links)
Transposase (← links)
R17 bacteriophage (← links)
Anneal (← links)
Lead hydroxide stain (← links)
Avian leukaemia virus (← links)
Post-transcriptional processing (← links)
Rna virus (← links) ...

See also: Trans, Antisense, Sense, RNA, Protein

Biology AntisenseAntisense strand

 
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