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AP site

Biology AP endonucleaseAP-1

AP site
An AP site, also known as an abasic site, is a location in DNA that has neither a purine nor pyrimidine base, usually due to DNA damage.
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AP site Apurinic or apyrimidinic site resulting from the loss of a purine or pyrimidine residue from the DNA.
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AP site
A molecule of single-stranded or double-stranded DNA missing a purine or pyrimidine base.
Aporepressor
A protein that requires binding of a small molecule co-repressor to negatively regulate gene expression.

Depurination - Loss of a purine base (A or G) to form an apurinic site (AP site).
Deamination - Hydrolysis changes a normal base to an atypical base containing a keto group in place of the original amine group.

See also: DNA, Pyrimidine, Purine, Site, Class

Biology AP endonucleaseAP-1

 
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