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Base sequence

Biology Base pairBase sequence analysis

Base sequence: The order of bases in a DNA molecule.
Base sequence analysis: A method, sometimes automated, for determining the sequence of bases in a strand of DNA.
Biotechnology: The use of biologic al processes to manufacture products.

 


Base sequence: The order of nucleotide bases in a DNA molecule.
Base sequence analysis: A method, sometimes automated, for determining the base sequence.

Base sequence The order of nucleotide bases in a DNA molecule; determines structure of proteins encoded by that DNA.
Base sequence analysis A method, sometimes automated, for determining the base sequence.

Base sequence analysis
A method, sometimes automated, for determining the base sequence.
Related Terms:
Base sequence
The order of nucleotide bases in a DNA molecule. Length is usually defined as the number of base pairs. Cf.

Base sequence
The order of nucleotide bases in a DNA molecule. Length is usually defined as the number of base pairs. Cf. sequence, DNA sequence.
Sequence
Order of bases in DNA or RNA (base sequence)or of amino acids in a protein.

The three-base sequence in tRNA complementary to a codon on mRNA. A nucleotide triplet in a tRNA molecule that aligns with a particular codon in mRNA under the influence of the ribosome, ...

Sequence See base sequence.
Sequence tagged site (STS) Short (200 to 500 base pairs) DNA sequence that has a single occurrence in the human genome and whose location and base sequence are known.

triplet Three-base sequence of mRNA that codes for a specific amino acid or termination codon. PICTURE
trisomy A condition where a cell has an extra chromosome.

Base sequence -- a partnership of organic bases found in DNA and RNA; adenine forms a base pair with thymine (or uracil) and guanine with cytosine in a double-stranded nucleic acid molecule.

Changes in the base sequence of a DNA molecule resulting from the random integration of DNA from another source. See DNA, Mutation. In situ. Refers to performing assays or manipulations with intact tissues. Insulin.

Back translation Use of the experimentally determined amino acid sequence of part or all of a polypeptide to determine the theoretical nucleic acid base sequence(s) which could code for it. This is normally done using a computer programme.

"Use of thermal denaturation studies to investigate the base sequence of yeast serine sRNA". Proc Natl Acad Sci U S A 51: 818-26. PMID 14172997.
^ Lodish H, Berk A, Matsudaira P, Kaiser CA, Krieger M, Scott MP, Zipursky SL, Darnell J.

We now can refine that definition: a mutation is a change in the DNA base sequence that results in a change of amino acid(s) in the polypeptide coded for by that gene.

Restriction enzymes always cut at the same base sequence. Because no two individuals have identical DNA, no two individuals will have the same length fragments. For example, the enzyme EcoRI always cuts DNA at the sequence GAATTC.

Nucleic acid molecules with the same base sequence except for minor differences in alleles; (ii) nucleic acid molecules originating from strains of the same species, thus having at least long stretches of identical DNA base sequences; ...

Homeobox A short stretch of nucleotides whose base sequence is virtually identical in all the genes that contain it. Homeoboxes have been found in many organisms from fruit flies to human beings.

The DNA base sequence carries the information a cell needs to assemble protein and RNA molecules. DNA sequence information is important to scientists investigating the functions of genes.

The order is determined by the base sequence of nucleotides in the gene that codes for the protein. Proteins are required for the structure, function, and regulation of the body's cells, tissues, and organs; and each protein has unique functions.

Insertion mutations. Changes in the base sequence of a DNA molecule resulting from the random integration of DNA from another source. See DNA, Mutation.
In situ. Refers to performing assays or manipulations with intact tissues.

Consensus sequence Idealized base sequence that represents common features of a promoter site.
Conservative substitutions Mutations that replace one amino acid with another similar in size and chemical properties.

" A large starting population of molecules (typically nucleic acids) that varies randomly in base sequence and shape is subjected to replication with variation, followed by selection.

degeneracy The genetic code is said to be degenerate because more than one three-base sequence in DNA can code for one amino acid.
degeneration The death or functional impairment of cells connected to destroyed or severely damaged neurons.

a defined segment of DNA or RNA, usually carrying a radioactive label, used to identify a specific segment of DNA that carries the complementary base sequence
Source: Jenkins, John B. 1990. Human Genetics, 2nd Edition. New York: Harper & Row ...

What that means, then is that that identifies a region which is functionally important. That is, if you change the base sequence of the DNA in that particular region, you alter the function of the gene. And so those have been maintained.

See also: Sequence, Base, DNA, Molecule, Nucleotide