Binding site
Specific DNA/RNA sequences a protein or protein complex bind. Some examples of protein binding sites are promoters, ribosome entry sites, and replication origins.
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binding sites Areas on the ribosome within which tRNA-amino acid complexes fit during protein synthesis.
binding site A DNA sequence to which a protein ,such as a transcription factor, binds.
Biological Replicate True for replicate hybridizations that use samples obtained from different RNA extracts from different biological material ...
Binding site: A place on cellular DNA to which a protein (such as a transcription factor) can bind.
The binding site for RNA polymerase is called the promoter. In bacteria, two features of the promoter appear to be important: ...
Ribosome binding site
A short nucleotide sequence upstream of a gene which forms the site on the mRNA molecule where the ribosome binds. (Also called a Shine-Delgarno sequence.) ...
Ribosome-binding site. The region of an mRNA molecule that binds the ribosome to initiate translation.
Receptors that have binding sites for the steroid androgen. Androgen receptors are altered in people with spinobulbar muscular atrophy (SBMA).
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z ...
A region of DNA extending 150-300 bp upstream from the transcription start site that contains binding sites for RNA polymerase and a number of proteins that regulate the rate of transcription of the adjacent gene.
"Structure, function and properties of antibody binding sites". J Mol Biol 217 (1): 133-51. PMID 1988675.
^ Fanning LJ, Connor AM, Wu GE (1996). "Development of the immunoglobulin repertoire". Clin. Immunol. Immunopathol. 79 (1): 1-14.
Currently there is an acute need for effective methods for locating genes in DNA sequences, along with their splice sites and regulatory binding sites, and for classifying new proteins by their predicted structure or function.
At pH 7, the C-terminus of DnaK(387-552) mimics substrate by binding to its own substrate-binding site, as has been observed previously for truncated Hsp70 constructs.
PromoterA short base sequence which is positioned close to the 5" end of a gene and acts as a recognition and binding site for the RNA polymerase complex prior to transcription of the gene.
RAPD Random amplification of polymorphic DNA.
There are three adjacent tRNA binding sites on a ribosome: the aminoacyl binding site for a tRNA molecule attached to the next amino acid in the protein (as illustrated in Figure 1), ...
The promoter and ribosome binding site codes in Eukaryotic DNA are likely to be different than those used by the host organism.
(Science: immunology) a thermodynamic expression of the strength of interaction between a single antigen binding Site and a single antigenic determinant (and thus of the stereochemical compatibility between them), ...
The next genes in this developmental cascade, the "gap genes," possess binding sites for this transcription factor. Gap genes are so named because mutations in these genes can produce larvae with "gaps" (missing several segments).
New tRNAs bring their amino acids to the open binding site on the ribosome/mRNA complex, forming a peptide bond between the amino acids. The complex then shifts along the mRNA to the next triplet, opening the A site. The new tRNA enters at the A site.
Examples include binding sites for transcription factors and splicing machinery.
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Nucleotide ...
Receptors are proteins with specific binding sites for signaling molecules called ligands. Membrane soluble ligands include steroid hormones (estrogen) which bind to cytoplasmic receptors.
Chromatin immunoprecipitation (chip) A technique for identifying the binding sites of dnabinding proteins. The protein is cross-linked to DNA to which it is bound in chromatin, and the DNA is fragmented into small pieces.
A conserved sequence 25 to 30 base pairs upstream from the site for transcription in many but not all genes; binding site for general factors involved in initiation of transcription. In prokaryotes the analogous is called Pribnow box.
Related Terms: ...
an operator (the switch)
a promoter (a binding site for the transcription enzyme).
The switch of an operon (that is, the "operator") is turned on unless a specific substance is bound to the operator. This substance is therefore called a repressor.
CONFORMATIONAL EPITOPE - An epitope which is dependent upon folding of a protein; amino acid residues present in the antibody binding site are often located at sites in the primary sequence of the protein which are at some distance from each other.
A regulatory region a short distance upstream from the 5' end of a transcription start site that acts as the binding site for RNA polymerase. A region of DNA to which RNA polymerase binds in order to initiate transcription.
A promoter is a sequence of DNA needed to turn a gene on or off. The process of transcription is initiated at the promoter. Usually found near the beginning of a gene, the promoter has a binding site for the enzyme used to make a messenger RNA (mRNA) ...
Cell-surface receptors such as the acetylcholine receptor and the insulin receptor, are located in the plasma membrane, with their ligand-binding site exposed to the external medium.
As the cycles continue, the number of possible primer binding sites doubles each time. Therefore in a short amount of time a negligible amount of DNA can be amplified to a workable quantity.
Unfortunately, an increasing threat is now Methicillin-Resistant Staph aureus (MRSA) which avoids methicillin and other β-lactams by an alteration in MRSA's penicillin target-binding site.
 See also: Protein, Trans, Site, Molecule, Proteins
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