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bottleneck effect Changes in gene frequency that result when numbers in a population are drastically reduced, and genetic variability is reduced as a result of the population being built up again from relatively few surviving individuals.
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A bottleneck in gel-based systems is the manual gel-preparation step, which is both time consuming and a potential source of variability in DNA sequencing.
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Well, genetic bottlenecks have to do with the question of how much genetic variability there might be in a population.
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The result is that the small surviving population is unlikely to be representative of the original population in its genetic makeup - a situation known as the bottleneck effect....
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See also: Human, Environment, Sequence, Genome, DNA
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