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Centromere

Biology CentriolesCentrosome

centromere
a region of a chromosome where it attaches to a spindle fiber during mitosis and meiosis
Source: Noland, George B. 1983. General Biology, 11th Edition. St. Louis, MO. C. V. Mosby ...

 


Centromere
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Centromere
The point where the two identical chromatids are connected during mitosis/meiosis.
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Centromere
The centromere is a region of a eukaryotic chromosome where the kinetochore is assembled. Thus, it is the site where spindle fibers of the mitotic spindle attach to the chromosome during mitosis.

Centromere
[Gr. kentron - point, spine, center of a circle; Gr. meros - a part]. The region of a chromosome where two chromatids are joined and where spindle fibers attach during mitosis and meiosis.

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Definition of centromere :
A kinetochore; the constricted region of a nuclear chromosome, to which the spindle fibres attach during division.   ...

Centromere
A centromere is a constricted region of a chromosome that separates it into a short arm (p) and a long arm (q). During cell division, the chromosomes first replicate so that each daughter cell receives a complete set of chromosomes.

Centromere Research
Moyzis was also cited for his ongoing explorations in identifying the functional human centromere, a region of the chromosome that plays a key role during cell division.

centromere - constriction in an unreplicated chromosome which results in two regions or arms ; serves as an attachment site for sister chromatids and spindle fibers .

Centromere
The region of a eukaryotic chromosome responsible for attachment to the mitotic or meiotic spindle leading to controlled partitioning of chromosomes during nuclear division.

Centromere The point at which a chromosome attaches to the spindle fibres during cell division. Visible as a constriction in the thickness of a metaphase chromosome.

centromere A specialized region on each chromatid to which kinetochores and sister chromatids attach. PICTURE
cephalization The concentration of sensory tissues in the anterior part of the body (head).

Centromere. The central portion of the chromosome to which the spindle fibers attach during mitotic and meiotic division.
Chemotherapy. A treatment for cancers that involves ad- ministering chemicals toxic to malignant cells.

centromere - see kinetochore.
centrosome - microtubule organizing center that contains the centriole; it divides and organizes the poles of the mitotic spindle apparatus during mitosis.

centromere
(sen-tro-mere) [Gk. kentron, center + meros, a part]
The centralized region joining two sister chromatids.
centrosome ...

Centromere the central region of a chromosome which holds the sister chromatids together
(centro = center; mer = part)
Cerebellum the wrinkled-looking‚ posterior part of the brain
(cereb = the brain; -elle = small) ...

centromere
The centralized region joining two sister chromatids.
Covered in BIOL1020 Lab 6 Mitosis & Meiosis
cephalic
Pertaining to the head.

Centromere: Constricted region where sister chromatids are attached in mitotic chromosomes. The centromere is generally flanked by repetitive DNA sequences and it is late to replicate. The centromere is an A-T region of about 130 bp.

Centromere The attachment site of mitotic spindles in chromosomes.
Ceramide (N-acyl sphingosine) A sphingosine with a long-chain acyl group attached to the amino group.

Centromere
The term introduced by Darlington (1936) for the specialized chromosome region which reacts to the spindle at nuclear division and to which spindle fibers attach during cell division. Appears as a distinct "waist" by microscopy.

Centromere interference: the inhibitory effect of the centromere upon crossing over in adjacent chromosomal regions.
Related Terms:
Crossing over ...

Centromere
- A single differentiated region of the chromosome which acts as the point of association between the chromosome and the spindle; also called kinetochore or primary constriction
Chloropidae ...

centromeres and
telomeres
is densely-packed;
is greatly enriched with transposons and other "junk" DNA;
is replicated late in S phase of the cell cycle;
has reduced crossing over in meiosis.

centromere Constricted region of a mitotic chromosome that holds sister chromatids together; also the site on the DNA where the kinetochore forms and then captures microtubules from the mitotic spindle.

A chromosome whose centromere lies between its middle and its end but closer to the middle.
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z ...

Centromere -- a region of a chromosome to which spindle traction fibers attach during mitosis and meiosis; the position of the centromere determines whether the chromosome is considered an acrocentric, metacentric or telomeric chromosome.

Artificial chromosomeA vector constructed from host cell chromosomal elements such as origin of replication, telomeres and centromere (in eukaryotes).

Protein complexes that form kinetochores in the centromere regions of sister chromatids are attached to specific repetitive DNA sequences, known as satellite DNA, which are similar in each chromosome.

Autosomes resemble each other in size and placement of the centromere, for example pairs of chromosome 21 are the same size, while pairs of chromosome 9 are of a different size from pair 21.

Metaphase is defined as the phase of mitosis when the centromeres and kinetochores are pulled and pushed into the center of the cell.

Each chromosome pair has a centromere. The centrioles also begin their journey to opposite sides of the cell. In Metaphase II all of the chromosomes line up along the center of the cell and the centrioles are in position for the duplication.

The analysis involves comparing chromosomes for their length, the placement of centromeres (areas where the two chromatids are joined), and the location and sizes of G-bands.

The diagram below is a portion of a double-stranded chromosome showing the centromere and a portion of the base sequence. The diagram does not show the extensive looping and coiling and the proteins associated with coiling.

Some mitotic spindle fibers elongate from the centrosomes and attach to kinetochores, protein bundles at the centromere region on the chromosomes where sister chromatids are joined.

Genomic DNA in fragments of 200-500 kb are linked to sequences which allow them to propagate in yeast as a mini-chromosome (including telomeres, a centromere and an ARS - an autonomous replication sequence).

See also: Chromosome, Chromosomes, Cell, Cells, DNA