Home (Chromosome walk)


  » »

Chromosome walk

Biology  Chromosome  Chromosome walking

Chromosome walking
Chromosome walking is a technique to clone a gene (e.g., a disease gene) from its known closest markers. The closest linked marker (e.g., EST or a known gene) to the gene is used to probe a genomic library.

Chromosome walking is a method in genetics for identifying and sequencing long parts of a DNA strand, e.g., a chromosome.

Chromosome walking
A technique used to identify a series of overlapping restriction fragments, often to determine the relative positions of genes on large chromosomes.

Chromosome walking. Working from a flanking DNA marker, overlapping clones are successively identified that span a chromosomal region of interest. (See Chromosome.) ...

Chromosome walking
Method involving hybridizing a primer of known sequence to a clone from an unordered genomic library and synthesizing a short complementary strand (called walking along a chromosome).

Chromosome walking: A technique for cloning everything in the genome around a known piece of DNA (the starting probe).

(Redirected from Chromosome walking)
Jump to: navigation, search
This article does not cite any references or sources. (August 2006)
Please help improve this article by adding citations to reliable sources.

Starting at DNA clones from both ends of this region, the researchers used chromosome walking to clone all of the interval; several candidate genes were identified within the region but rejected as the cause of CF.

See also: See also: DNA, Chromosome, Chromosome walking, Strand, Sequence

Biology  Chromosome  Chromosome walking

RSS Mobile