class switching
in an antibody producing cell, a switch in the class of antibody being synthesized
Source: Jenkins, John B. 1990. Human Genetics, 2nd Edition. New York: Harper & Row ...
Class switching: The process by which a IgM or IgD producing B lymphocyte switches to produce one of the secondary immunoglobulins (IgG, IgA or IgE) with the same antigen binding specificity.
Class switching A step in the differentiation of an antibody-producing cells in which the cells switch from producing igm antibodies to producing one or the other classes of antibodies while maintaining the same antigen specificity.
[edit] Class switching
Isotype or class switching is a biological process occurring after activation of the B cell, which allows the cell to produce different classes of antibody (IgA, IgE, or IgG).
help B cells make IgE antibodies by synthesizing interleukin 4 (IL-4) and interleukin 13 (IL-13), which promote class switching.
 See also: Antibody, Class, Human, Cells, Cell
  
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