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Cleavage

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cleavage
division of a zygote into cells known as blastomeres
Source: Noland, George B. 1983. General Biology, 11th Edition. St. Louis, MO. C. V. Mosby ...

 


Cleavage
[Anglo-Saxon cleofian - to cut, divide]. The process of cell division in the zygote to form a multicellular embryo.

The cleavage process in molluscs and some invertebrates whereby orientation of the spindle at mitosis is at an angle to the original egg axis.
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z ...

Hydrolytic cleavage --> hydrolysis
(Science: chemistry) The splitting of a compound into fragments by the addition of water, the hydroxyl group being incorporated in one fragment and the hydrogen atom in the other.
Origin: gr. Lysis = dissolution ...

Cleavage
Mitosis and cytokinesis of the zygote, an unusually large cell, produces an increasing number of smaller cells, each with an exact copy of the genome present in the zygote. However, the genes of the zygote are not expressed at first.

Cleavage strategies. Combinations of methylases, restriction enzymes, and DNA binding proteins can be used to cut genomic DNA at very specific sites.

cleavage furrow A constriction of the cell membrane at the equator of the cell that marks the beginning of cytokinesis in animal cells. The cell divides as the furrow deepens.

Cleavage
Cleavage is the first step in development of ALL multicelled organisms. Cleavage converts a single-celled zygote into a multicelled embryo by mitosis. Usually, the zygotic cytoplasm is divided among the newly formed cells.

cleavage furrow
The first sign of cleavage in an animal cell; a shallow groove in the cell surface near the old metaphase plate.
cline ...

cleavage
The process of cytokinesis in animal cells, characterized by pinching of the plasma membrane; also, the succession of rapid cell divisions without growth during early embryonic development that converts the zygote into a ball of cells.

cleavage The early mitotic and cytoplasmic divisions of an embryo.
Cleido- Key, clavicle.
climacteric rise A point during the ripening process of certain fruit when the respiration rates rise to very high levels.

Sites of cleavage
Rather than cutting DNA indiscriminately, a restiction enzyme cuts only double-helical segments that contain a particular nucleotide sequence, ...

discoidal cleavage - incomplete division of the blastodisc, a region of yolk-free, active cytoplasm; characteristic of birds, fishes and reptiles.

Telophase I: CLEAVAGE FURROW forms beginning the process of CYTOKINESIS (cell division). Resulting daughter cells are HAPLOID (1N).
Prophase II: Spindle formation begins and centrosomes begin moving toward poles.

The spontaneous cleavage of the N glycosidic link between purine bases and deoxyribose in DNA.

In addition to those listed above, the most important modification of primary structure is peptide cleavage (See: Protease).

In most cases, the cleavage furrow is formed near the equator of the parent cell so that it divides symmetrically into daughter cells of equal size.

by Sanger, DNA is synthesized in vitro in such a way that it is radioactively labeled and the reaction terminates specifically at the position corresponding to a given base; the "chemical" method, ssDNA is subjected to several chemical cleavage ...

A reaction in which a molecule of water is added at the site of cleavage of a molecule to two products. I Immortalizing oncogene. A gene that upon transfection enables a primary cell to grow indefinitely in culture.

The roles of different proteolytic enzymes in this process can be determined from the sites of cleavage in the aggrecan core protein, which generates novel termini (neoepitopes).

Beard, 176 on the other hand, maintains that in the skate they are not derived from this epithelium, but are probably formed during the later stages of cell cleavage, before there is any trace of an embryo; ...

The cell division by which the fertilized egg produces the early embryo is called cleavage. During cleavage there is no cell growth between the cell divisions because the egg contains a very large amount of cytoplasm.

One of the most common of these cleavages is the removal of specific signal peptides. These peptides target proteins for transport to a particular cellular organelle in a process known as protein sorting.

Several different classes of restriction endonucleases can be differentiated based upon their binding and cleavage sites and their required cofactors.

RESTRICTION ENDONUCLEASE - A bacterial enzyme which recognizes a specific palindromic sequence (recognition sequence) within a double-stranded DNA molecule and then catalyzes the cleavage of both strands at that site. Also called a restriction enzyme.

Cytokinesis (division of the cytoplasm) begins in anaphase. A cleavage furrow forms as actin filaments underneath the plasma membrane constrict in a band called the contractile ring. Two cells will be produced as this process continues.

the number of internal restriction endonuclease cleavage sites for the enzyme HaeIII
B.
the number of protein coding genes ...

Glycogen degradation The cleavage of glycogen by phosphorolysis, catalyzed by glycogen phosphorylase, to yield glucose 1-phosphate, which can be converted into glucose 6-phosphate.

restriction map - diagrammatic representation of a DNA molecule indicating the sites of cleavage by various restriction enzymes ...

Hydrolysis. A reaction in which a molecule of water is added at the site of cleavage of a molecule to two products.
I ...

amino acid sequence Amino acid sequences for proteins from the start of translation to the terminator. Unless specifically noted, the sequences contain all amino acids present before any post translational modification occurs (e.g. cleavage of ...

Post-translational processing: The reactions which alter a protein's covalent structure, such as phosphorylation, glycosylation or proteolytic cleavage.
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See also: Cells, Cell, Organ, Trans, Protein