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Coding sequence

Biology Coding regionCoding strand

Coding Sequence (CDS): 444 base pairs within the mRNA code for the amino acid sequence of the gene's protein product.

 


Coding sequence That part of a gene which contains the codons which will, via a mRNA intermediate, be translated into polypeptide. Its antithesis is non-coding sequence.

Coding sequence (cds): The portion of a gene that is transcribed into mRNA and translated into protein.
Codominance: Equal effect on the phenotype of two alleles of the same locus (as opposed to recessive and dominant).

Coding sequence: The portion of a gene or an mRNA which actually codes for a protein. Introns are not coding sequences; nor are the 5' or 3' untranslated regions (or the flanking regions, for that matter - they are not even transcribed into mRNA).

The process of producing a protein from its DNA- and mRNA-coding sequences. Gene flow. The exchange of genes between different but (usually) related populations. Gene frequency. The percentage of a given allele in a population of organisms.

"The mutation causing the black-and-tan pigmentation phenotype of Mangalitza pigs maps to the porcine ASIP locus but does not affect its coding sequence". Mammalian Genome 17: 58-66. PMID 16416091.
^ "at Spontaneous Allele Detail".

Eukaryotic DNA contains both exons (coding sequences) and introns (intervening sequences). In eukaryotic cells this DNA is used as a template for the production of mRNA, which must then undergo mRNA splicing.

A mutation which adds or deletes one or two base pairs (or any non-multiple of 3) from a coding sequence in a molecule of DNA, so that the genetic code is read out-of-phase.

The DNA base sequence interrupting the protein-coding sequences of a gene; intron sequences are transcribed into RNA but are cut out of the message before it is translated into protein.

If the sequence is altered by snipping or swapping the result is likely to be fatal because the coding sequence [the readout in terms of triplets] will be messed up.

any non-intron section of the coding sequence of a gene; together, the exons constitute the mRNA and are translated into protein
Source: Jenkins, John B. 1990. Human Genetics, 2nd Edition. New York: Harper & Row
...

Almost half the DNA in eukaryotic cells is repeated nucleotide sequences. Protein-coding sequences are interrupted by non-coding regions. Non-coding interruptions are known as intervening sequences or introns.

A specific loci may contain one of several different coding sequences.
e.g. Many genes have slightly different coding sequences between chromosomes
Macrosatellites also show a similar sequence diversity ...

Transfer RNA (tRNA) A class of RNA having structures with triplet nucleotide sequences that are complementary to the triplet nucleotide coding sequences of mRNA.

Intron: The DNA base sequence interrupting the protein coding sequence of a gene; this sequence is transcribed into RNA but is cut out of the message before it is translated into protein. Compare exon.
In vitro: Outside a living organism.

Problem 8: Protein coding sequences
The regions of DNA in a eukaryotic gene that encode a polypeptide product are called:
A.
hnRNAs ...

With gene splicing, the promoter of a gene whose expression you wish to monitor can be coupled to the coding sequence of a chosen "reporter" gene.
lacZ
One favorite reporter gene is the Z gene of the E.

An abundant class of molecules consisting of a non-coding sequence of approximately 22 nucleotides. miRNA controls gene expression at the post-transcriptional level.
Related
siRNA ...

A class of RNA having structures with triplet nucleotide sequences that are complementary sequences to the triplet nucleotide coding sequences of mRNA.

Allozymes may result from point mutations or from insertion-deletion (indel) events that affect the DNA coding sequence of the gene. As with any other new mutation, there are three things that may happen to a new allozyme: ...

Gene expression. The process of producing a protein from its DNA- and mRNA-coding sequences.
Gene flow. The exchange of genes between different but (usually) related populations.

by increasing or decreasing its rate of RNA synthesis (via effects on binding and transcription of the basal transcription apparatus including RNA Polymerase); can be located upstream (5'), downstream (3') or within the protein coding sequence of the ...

See also: Sequence, DNA, Trans, Gene, Protein