Competitive inhibition

Competitive inhibition is a form of enzyme inhibition where binding of the inhibitor to the enzyme prevents binding of the substrate and vice versa.
Contents
1 Mechanism
2 Equation
3 Derivation
4 see also ...

Competitive inhibition
(Science: chemistry) inhibitor that occupies the active site of an enzyme or the binding Site of a receptor and prevents the normal substrate or ligand from binding.

Competitive Inhibition
In the presence of a competitive inhibitor, it takes a higher substrate concentration to achieve the same velocities that were reached in its absence.

Competitive Inhibition works by the competition of the regulatory compound and substrate for the binding site. If enough regulatory compound molecules bind to enough enzymes, the pathway is shut down or at least slowed down.

Competitive Inhibition
In competitive inhibition, a similar-shaped molecule competes with the substrate for active sites.
Noncompetitive Inhibition ...

Competitive inhibition The reduction in the rate of enzyme activity observed when the enzyme can bind the substrate or the inhibitor but not both.

In noncompetitive inhibition, the inhibitor works by occupying some other site on the enzyme. Because of this, the substrate and inhibitor do not compete for access to the same site.

End-products accumulate within the cell and stop the reaction when sufficient product is made
This is achieved by non-competitive inhibition by the end-product
The enzyme early in the reaction pathway is inhibited by the end-product ...

See also: Enzyme, Molecule, Substrate, Site, Enzymes