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Complement

Biology  Competitive inhibitor  Complementary DNA

complementary
Referring to two nucleic acid sequences or strands that can form a perfect base-paired double helix with each other; ...


Complementary
Supplying a defect or helping to do so, making complete, accessory.
Origin: L. Complere = to fill ...

complementary DNA (cDNA)
cDNA is DNA copied from message RNA (mRNA).
Related ...

complementary DNA (cDNA) Synthetic DNA reverse transcribed from a specific RNA through the action of the enzyme reverse transcriptase. DNA synthesized by reverse transcriptase using RNA as a template.

Complementary pathways in mammalian female sex determination
Serge Nef* and Jean-Dominique Vassalli
Include ...

The Complement System
Overview
Sometimes the interaction of antibodies with antigen is useful by itself. For example, ...

Complementary base pair: a pair of bases in which the identity of one base defines the identity of its partner base. E.g.: In a DNA molecule there are two complementary base pairs--Adenine and thymine, and guanine and cytosine.

Complementary sequence: A sequence of bases that can form a double-stranded structure by matching base pairs. The complementary sequence to G-T-A-C, for instance, is C-A-T-G. Cytosine (C): A base; one of the molecular compon ents of DNA and RNA.

Complement proteins - plasma proteins which have a role in nonspecific and specific defenses
Form a cascade effect - if only a few are activated, they will trigger others to become active in great numbers ...

Complementation
The ability of a gene to produce a functional gene product which compensates for the mutant phenotype caused by a mutation in another gene. Typically, the complementing gene produces a gene product (e.g.

Complementary nucleotides. Members of the pairs adenine-thymine, adenine-uracil, and guaninecytosine that have the ability to hydrogen bond to one another. (See nucleotide.) ...

complementary nucleotides The bonding preferences of nucleotides, Adenine with Thymine, and Cytosine with Guanine. Also referred to as complementary base pairing. PICTURE ...

complement fixation
An immune response in which antigen-antibody complexes activate complement proteins.
complement system ...

Complementation: The production of a wildtype phenotype when two recessive mutations from different genes are brought together.

complementary DNA (cDNA) /kom-plÉ™-MENT-er-ee/ A DNA sequence generated from an RNA (usually mRNA) template. If the introns have been processed out of the RNA, the resulting cDNA will differ from the gene that originally produced the RNA.

Complementary - Term used to refer to the natural pairing of the nitrogen bases within DNA and RNA. In DNA, cytosine pairs with guanine and adenine with thymine. In RNA, the thymine is replaced with uracil, which pairs with adenine.

Complementarity and Replication
Each strand of DNA has a direction in which it can be read by the cellular machinery, arising from the arrangement of phosphates and sugars in the
A helix-loop-helix dimer bound to DNA.

Complementary sequence
Nucleic acid base sequence that can form a double-stranded structure with another DNA fragment by following base-pairing rules (A pairs with T and C with G). The complementary sequence to GTAC for example, is CATG.

[edit] Complement system
Main article: Complement system
The complement system is a biochemical cascade of the immune system that helps clear pathogens from an organism.

Complementation
The process by which two recessive mutants can supply each other's deficiency, such that a heterokaryon or diploid derived fron them and having the trans (repulsion) configuration is phenotypically normal (wild-type) or nearly so.

Complementation test
A mating test to determine whether two different recessive mutations (a1;a2) on opposite chromosomes (trans, a1+/+a2) of a diploid or partial diploid will not complement (ie have a mutant phenotype) each other; ...

Complementary base pairing is very important in the conservation of the base sequence of DNA. This is because adenine always pairs up with thymine and guanine always pairs up with cytosine.

Complement fixation test
a serologic procedure to detect antibodies which combine with specific antigen in the presence of complement ...

Complement and antibodies are both components of the immune system that jointly help in fighting infection and foreign tissue. Here, antibody and complement work together to lyse these "foreign" red blood cells.
3.6 Human platelets crawling on glass ...

complementary base pairs - base-pairing between a larger purine base (adenine or guanine) and a smaller pyrimidine base (cytosine or thymine) while DNA is in its double-helix. (A/T, G/C) ...

Complementation
- Process by which genes on different DNA molecules interact. Usually a protein product is involved, as this is a diffusible molecule that can exert its effect away from the DNA itself.

complement fixation test Immunological method used to detect presence of antibodies that bind (or fix) complement; a standard diagnostic test for many infections.

The complement system directly kills microbes, supplements inflammatory response, and works with the immune response. It complements the actions of the immune system.

The complementary RNA molecule is synthesized according to base-pairing rules, except that uracil is the complementary base to adenine.

Fragment complementarity and splicing
Because recognition sequences differ between restriction enzymes, the length and the exact sequence of a sticky-end "overhang", as well as whether it is the 5' or the 3' strand that overhangs, ...

cDNA
A complementary DNA is a single stranded DNA synthetised from messenger RNA, by reverse transcriptase. It has the complementary base sequence of that mRNA. It must be distinguished from the complementary strand of a double stranded DNA.

it depends on complementary base pairing
B.
a polysaccharide can hybridize with a DNA strand ...

Is the genetic complement of a neuron different from a skin cell or muscle cell?
This question was first approached by Briggs and King in the 1950s through nuclear transfer experiments in frogs.

See also: See also: DNA, Sequence, Trans, Protein, Molecule

Biology  Competitive inhibitor  Complementary DNA

 
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