Contiguous gene syndrome
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Contiguous gene syndrome A syndrome caused by a deletion which has removed one copy of a number of genes which are close together in the genome.
Contiguous gene syndromes: Disorders caused by microdeletions or microduplications in neighbouring functional genes. Inheritance is usually sporadic but recurrences are possible.
Contiguous gene syndrome
Syndrome due to abnormalities of 2 or more genes that map next to each other on a chromosome; most often caused by a deletion that involves several contiguous genes.
Related Terms:
Gene ...
Microdeletion Syndromes(contiguous gene syndromes, segmental aneusomy)
Mosaicism: Somatic, gonadal, placental ...
Due to the complex and variable expression of this disorder, it is thought that WHS is a contiguous gene syndrome with an undefined number of genes contributing to the phenotype.
 See also: Contig, Chromosome, Deletion, Segment, Trans
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