Cosmid map.
A high-resolution "sequence-ready" cosmid contig map comprises the next resolution level (average resolution, 5 kb) and consists of 4000 fingerprinted cosmids assembled into contigs covering 60% of the chromosome.
Cosmid A type of cloning vector which is based on a plasmid but which contains one copy (or sometimes two copies) of the lambda cohesive end.
cosmid A plasmid into which phage lambda cos sites have been inserted. As a result,the plasmid DNA can be packaged in vitro into the phage coat.
Cosmid
A cloning vector consisting of the phage lambda cos site inserted into a plasmid. Such vectors can be packaged into lambda phage or maintained as plasmids. Cosmids are often used to clone large DNA fragments (up to about 40 kilobases).
Cosmid
- A hybrid vector made up of plasmid sequences and the cohesive ends of the bacteriophage lambda
Cotton ...
COSMID - A genetically-engineered plasmid containing bacteriophage lambda packaging signals and potentially very large pieces of inserted foreign DNA (up to 50 kb) which can be replicated in bacterial cells.
Cosmid: A type of vector used for cloning 35-45 kb of DNA. These are plasmids carrying a phage l cos site (which allows packaging into l capsids), an origin of replication and an antibiotic resistance gene.
Cosmids -- plasmid vectors designed for cloning large fragments of eukaryotic DNA; the vector is a plasmid into which phage lambda cohesive end sites have been inserted. CpG islands -- areas of multiple CG repeats in DNA.
Examples are plasmids, cosmids, and yeast artificial chromosomes; vectors are often recombinant molecules containing DNA sequences from several sources.
cM See centimorgan.
CosmidAn artificial hybrid vector into which large (~40kbp) DNA fragments can be inserted; this makes it useful in genomic library preparation.
Individual primary recombinant clones (hosted in phage, cosmid, YAC, or other vector ) that are placed in two-dimensional arrays in microtiter dishes.
Fosmids are similar to cosmids but are based on the bacterial F-plasmid. The cloning vector is limited, as a host (usually E. coli) can only contain one fosmid molecule. Fosmids are 40 kb.
Arrayed library Individual primary recombinant clones (hosted in phage, cosmid, YAC, or other vector) that are placed in two-dimensional arrays in microtiter dishes.
cloning vector - intentionally designed artificial DNA construct used by molecular biologists to amplify selected pieces of DNA inserted into the construct; examples include plasmid, phage, phagemid, cosmid, fosmid, ...
DNA fragment of appropriate size can be integrated without loss of the vectors capacity for self-replication; vectors introduce foreign DNA into host cells, where it is replicated autonomously in large quantities. Examples are plasmids, cosmids, ...
 See also: Genome, Sequence, Chromosome, DNA, Human
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