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Crossing over

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crossing over
the exchange of genetic material between members of a homologous chromosome pair
Source: Jenkins, John B. 1990. Human Genetics, 2nd Edition. New York: Harper & Row ...

Crossing Over and Genetic Recombination in Meiosis
Crossing over occurs between equivalent portions of two nonsister chromatids.
Link to an illustrated discussion of crossing over examined at the level of a cell undergoing meiosis.

Crossing Over and Genetic Diversity
- Genetics and Evolution
Gregor Mendel, an Austrian monk, is most famous in this field for his study of the phenotype of pea plants, including the shape of the peas on the pea plants.

Non-reciprocal crossing over caused by mismatching of homologous chromosomes. Usually occurs in regions of repetitive DNA.
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z ...

Crossing over is more likely to occur between genes that are far apart. The farther apart genes are, the greater the probability that crossing over will occur between them.
In the example above, we had 8% crossing over.

Crossing over
Main article: Chromosomal crossover
Crossing over of two chromosomes occurs during meiosis. After chromosomal replication, the four available chromatids are in tight formation with one another.

Crossing over was first described, in theory, by Thomas Hunt Morgan. The physical basis of crossing over was first demonstrated by Harriet Creighton and Barbara McClintock in 1931.[1]
Contents ...

crossing over: Where a section of one chromosome switches places with the same section from the other chromosome of the pair. This sometimes occurs when a germ cell makes copies of its chromosomes before dividing.

crossing over between sister chromatids either on the same or on homologous chromosomes
Source: Jenkins, John B. 1990. Human Genetics, 2nd Edition. New York: Harper & Row
What Topic Is Your BIOLOGY Paper On?
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Crossing over
The breaking during meiosis of one maternal and one paternal chromosome, the exchange of corresponding sections of DNA, and the rejoining of the chromosomes. This process can result in an exchange of alleles between chromosomes.

crossing over
The reciprocal exchange of genetic material between nonsister chromatids during synapsis of meiosis I.
cryptic coloration ...

crossing over A process in which homologous chromosomes exchange material through the breakage and reunion of two chromatids. A single crossover represents one reciprocal breakage and reunion event.

Unequal crossing over A crossover in which the chromosomal segments exchanged are not equally sized because the breakpoint has occurred at a different place on each homologue.

The exchange of DNA fragments between two DNA molecules or chromatids of paired chromosomes (during crossing over) at the site of identical nucleotide sequences. Homozygote.

In higher organisms, this can occur by crossing over.
Regulatory regions or sequences A DNA base sequence that controls gene expression.
Resolution Degree of molecular detail on a physical map of DNA, ranging from low to high.

After the DNA is replicated in the S phase preceding meiosis, the homologous chromosomes (each composed of two chromatids) pair up in Prophase I and then crossing over, ...

Centromere interference: the inhibitory effect of the centromere upon crossing over in adjacent chromosomal regions.
Related Terms:
Crossing over ...

Early in her career, she was the first to describe crossing over during meiosis in plants. At the peak of her career, she realized that genes were not immobile on the chromosomes, but could move and rearrange themselves with startling consequences.

A new combination of alleles resulting from the rearrangement occuring by crossing-over or by independent assortment (see crossing over).
Terms related to recombination
alternative splicing
centimorgan
crossing over
map unit
recombinational repair ...

Crossing over
The term coined by Morgan and Cattell (1912) for the occurrence of new combinations of linked characters.

An X-shaped crossing formed by the crossing over of homologous chromosomes during meiosis when genetic material is exchanged.

But having invented SRY the key driver of the evolution of the sex chromosomes was the shutting down of recombination of crossing over between this pair.

Recombination frequency. The frequency at which crossing over occurs between two chromosomal loci--the probability that two loci will become unlinked during meiosis.

The exchange of pieces of DNA during the formation of eggs and sperm. Recombination allows the chromosomes to shuffle their genetic material, increasing the potential of genetic diversity. Homologous recombination is also known as crossing over.

where pairs of homologous chromatids remain in contact during late prophase to anaphase of the first meiotic division. The chiasma indicates where an exchange of homologous segments has taken place between nonsister chromatids by crossing over.

This process is the molecular basis of crossing over during meiosis and some DNA repair mechanisms. Another form of recombination, site-specific recombination, is found where transfer, rearrangement or insertion of specific sections of DNA occurs e.

See also: Crossing, Chromosome, Chromosomes, DNA, Meiosis