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Deletion

Biology DehiscentDeme

Deletion
The loss of one or more bases or base pairs from a molecule of DNA.
Deletion mapping
The use of deletion mutations to determine the position of overlapping point mutations for fine structure mapping of a genetic locus.
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deletion
the loss of a chromosome segment
Source: Jenkins, John B. 1990. Human Genetics, 2nd Edition. New York: Harper & Row ...

File deletion, a way of removing a file from a computer's file system
Deletion (genetics), deletion of a gene or chromosome segment, symbolized in the literature by a " symbol ...

Loss of a DNA (chromosome) segment from a chromosome. Deletions are recognised genetically by: absence of reverse mutation
presence of a deletion loop at meiosis visualized cytologically
revealing of recessive lethals
pseudodominance ...

Deletion really means that something is missing. And as a geneticist talking about deletion it means something is missing of the genetic material.

Deletions are fragments of chromosomes that are missing. They are usually lethal when homozygous and cause abnormalities when heterozygous.
Radiation, viruses, chemicals, and unequal crossing-over may cause them.
Cri du Chat Syndrome ...

Deletion Studies
Eddy Rubin's group (Lawrence Berkeley National Laboratory, LBNL) uses the laboratory mouse to examine gene function, ...

deletion The loss of a chromosome segment without altering the number of chromosomes.
dendrites Short, highly branched fibers that carry signals toward the cell body of a neuron. PICTURE ...

deletion
(1) A deficiency in a chromosome resulting from the loss of a fragment through breakage. (2) A mutational loss of a nucleotide from a gene.
demography ...

Deletion
Loss of a segment of a chromosome as the genetical consequence of a transposition.
Insertion
Addition of a DNA element into a chromosome.

Deletion:
The absence of bases that are present in the wild-type DNA sequence.
Dideoxy Sequencing: ...

Deletion Mapping
Deletions can be mapped by the same procedure used for point mutations. Simply cross pairs of deletion mutants and see if they produce progeny that can grow on E. coli strain K.

deletion A mutation involving the removal of one or more base pairs in DNA sequence. Large deletions are visible as the lack of chromosomal segments.

deletion A mutation resulting from the loss of a small segment of DNA.
deletion mutant A mutation in which a base pair is deleted
delta Fan-shaped sediment deposit found at the mouth of a river.

Deletion A mutation resulting in the loss of normal DNA sequence. A deletion may be of any size from 1 nucleotide pair to the loss of most of a chromosome.

Deletion
A loss of part of the DNA from a chromosome; can lead to a disease or abnormality.
See also: chromosome, mutation
Deletion map ...

A deletion, substitution, or duplication of one or more bases that causes the reading-frame of a structural gene to shift from the normal series of triplets.

Microdeletion Syndromes(contiguous gene syndromes, segmental aneusomy)
Mosaicism: Somatic, gonadal, placental ...

Why is this deletion variant present in some populations in such high frequencies? HIV is, at most, a couple centuries old and, more likely, less than a hundred years old.

Additions and deletions
During copying a segment of DNA may be deleted or a new segment may be inserted. Typically this happens as a result of chromosome breakage or realignment.

INDEL Insertion/deletions (INDELS) are sequence variants where the Columbia (reference) polymorphism is an insertion relative to one ecotype and a deletion relative to another, different ecotype.

Name comes from the distinctive mewing cry of affected infants; characterized by significant mental deficiency, low birthweight, failure to thrive and short stature; deletion of a small section of the short arm of chromosome 5.

Example deletion mutation A mutation resulting from the deletion of one or more nucleotides from a gene. denaturation Alteration of the specific native conformation of a polypeptide chain, protein, or nucleic acid.

Cri du chat syndrome, which is caused by the deletion of part of the short arm of chromosome 5. Victims make high-pitched cries that sound like a cat. They have wide-set eyes, a small head and jaw and are mentally retarded.

Frameshift mutation - a mutation (deletion or insertion, never a simple substitution) of one or more nucleotides but never a multiple of 3 nucleotides, which shortens or lengthens a trinucleotide sequence representing a codon; ...

A general term for a deletion, duplication, or inversion of a chromosome segment, or an interchange of segments which may be between homologous or non-homologous chromosomes.
Related Terms:
Deletion ...

(fluorescence in situ hybridization): One of the more modern methods in cytogenetics, which uses fluorescence-labelled chromosome-specific DNA, probes to detect translocations, inversions, deletions, ...

- A mutation caused by either the insertion or deletion of a number od nucleotide pairs in DNA, the effect of which is a change in the reading frame of codens in an mRNA molecule during the protein synthesis, ...

The condition of a cell or of an organism that has additions or deletions of a small number of whole chromosomes from the expected balanced diploid number of chromosomes.

TATA box: A sequence found in the promoter (part of the 5' flanking region) of many genes. Deletion of this site (the binding site of transcription factor TFIID) causes a marked reduction in transcription, ...

Point mutation
A mutation involving the substitution, addition, or deletion of a single base pair .

Deletion mutation (← links)
Rice diet (← links)
Fimbriae bacterial (← links)
N protein (← links)
Reading frame open (← links)
Rearrangement (← links)
Actomyosin (← links)
Degp protease (← links) ...

See also: DNA, Sequence, Chromosome, Gene, Genome