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Differentiation

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Differentiation
The distinguishing of one thing or disease from another. The mathematical process of obtaining the derivative of a function.

 


differentiation
Definition of differentiation
A well-differentiated cell is highly specialized, structurally highly organized and clearly recognizable. A poorly differentiated cell is structurally poorly organized and difficult to recognize.

Differentiation can involve changes in numerous aspects of cell physiology; size, shape, polarity, metabolic activity, responsiveness to signals, and gene expression profiles can all change during differentiation.

Differentiation and Genetic Cascades
Development of a complex multicellular organism is more than just growth - we certainly do not look like gigantic fertilized eggs.

Differentiation
In time, the cells of the embryo differentiate to form the specialized structures and functions that they will have in the adult. They form neurons, blood cells, skin cells, muscle cells, etc., etc.

Differentiation between subpopulations, followed by migration among them, could contribute to adaptations amongst populations. Wright also came up with the idea of the adaptive landscape -- an idea that remains influential to this day.
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Differentiation: A process of development whereby properties of a cell or tissue become specialised for its particular task.
Diploid: the presence of two chromosomes of a pair in a cell.
Directed Mutation: see Adaptive Mutation ...

differentiation (L. differre, to carry different ways) A process in which unspecialized cells develop structures and functions characteristic of a particular type of cell.

differentiation - process whereby cells acquire their mature morphological and biochemical characteristics. Differentiation is often considered a 'final step' of development in which cells take on their mature function.

differentiation The chemical and physical changes associated with the developmental process of an organism or cell.

differentiation
Divergence in structure and function of cells as they become specialized during a multicellular organism's development; depends on the control of gene expression (cell differentiation).

Lack Differentiation
Normally, cells become differentiated and become capable of specific functions. For example, muscle cells are specialized for contraction, nerve cells (neurons) are specialized for conducting signals, etc.

zone of differentiation Area in plant roots where recently produced cells develop into different cell types.
zone of elongation Area in plant roots where recently produced cells grow and elongate prior to differentiation.

cellular differentiation
The structural and functional divergence of cells as they become specialized during a multicellular organism's development; dependent on the control of gene expression.
cellular respiration ...

Method of Differentiation Between Similar Protein Folds
Dubhashi, Kedarnath A.
FAKtory: A Customizable Fragment Assembly System ...

1-10 2 How transcriptional and epigenetic programmes are played out on an individual mammalian gene cluster during lineage commitment and differentiation Douglas R.

Sxl directs somatic sexual development by controlling the dosage compensation system (Lucchesi, 1978) and the somatic sexual differentiation pathway (reviewed by Cline and Meyer, 1996).

Morphogenesis (from the Greek morphę shape and genesis creation) is one of three fundamental aspects of developmental biology along with the control of cell growth and cellular differentiation.

differentiation Specialization of cell structure and function during embryonic growth and development. diffusion The net movement of molecules in the direction of lower concentration.

Thrinaxodon has a reduced number of incisors, a precursor to tooth differentiation. Cynognathus (a doglike carnivore) shows a further increase in size of the dentary bone. The other three bones are located inside the back portion of the jaw.

Segre's research focuses on the dynamic process by which the epidermis maintains a proper balance between proliferation and differentiation.

Process of evolutionary branching of basic forms into specialized forms by differentiation, specialization and adaptation. See adaptive radiation.
Related Terms:
Evolution ...

Parapatric speciation. The differentiation into distinct species of populations experiencing some gene flow
Parasite. An organism living on or in, and negatively affecting, another organism ...

Originating in embryology, today developmental biology studies the genetic control of cell growth, differentiation and "morphogenesis," which is the process that gives rise to tissues, organs and anatomy.

an embryonic tissue or organ that causes differentiation of another tissue or organ
Source: Noland, George B. 1983. General Biology, 11th Edition. St. Louis, MO. C. V. Mosby
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There are several levels of sexual differentiation: chromosomal sex (XX or XY), gonadal sex (testes or ovary), internal plumbing sex (fallopian tubes, uterus or vas deferens, seminiferous tubules, epididymis), external plumbing sex (labia, ...

Cladogenesis
Process of evolutionary branching of basic forms into specialized forms by differentiation, specialization and adaptation. See adaptive radiation.

High FST implies a considerable degree of differentiation among populations. FIS (inbreeding coefficient) is the proportion of the variance in the subpopulation contained in an individual. High FIS implies a high degree of inbreeding.

spermiogenesis The process of differentiation by which haploid spermatids are transformed into mature spermatozoa.

Proto-oncogene - a cellular oncogene-like sequence which is thought to play a role in controlling normal cellular growth and differentiation.

Nieuwkoop: "In my opinion, the central question in embryology is therefore the nature of competence, its formation, climax, and decline." From: R. Gordon, N.K. Bjorklund, P.D. Nieuwkoop. Appendix: Dialogue on embryonic induction and differentiation ...

See also: Organ, Trans, Cell, Cells, Protein