DNA methylation
A post-replication process. Cytosine residues in CpG sequences are methylated, forming gene-specific methylation patterns. Methylation of promoter regions correlates with gene expression patterns.
Related ...
DNA methylation
The addition of methyl groups (-CH3) to bases of DNA after DNA synthesis; may serve as a long-term control of gene expression.
DNA polymerase ...
DNA methylation in vertebrates The addition of a methyl group to a cytosine base of a CpG dinucleotide to form 5-methylcytosine. in micro-organisms many other methylation positions may be used.
[edit] DNA methylation and chromatin remodelling
DNA associates with histone proteins to form chromatin.
the number of DNA methylation sites
D.
the number of times a simple DNA sequence is repeated ...
At the replication fork, nucleosomes, transcription factors and RNA polymerases are stripped off the DNA, the DNA double strands are unzipped and DNA methylation marks may be erased.
In recent years, there has been rapid progress in understanding epigenetic mechanisms, which include differences in DNA methylation, as well as difference in chromatin structure.
See: methyl transferase and dNA methylation.
Please contribute to this project, if you have more information about this term feel free to edit this page ...
In comparing two sources of DNA, differences in restriction fragment patterns might, therefore, identify patterns of DNA methylation.
The shut-down of the XIST locus on the active X chromosome is done by methylating XIST regulatory sequences. DNA methylation usually results in gene repression so methylation permanently blocks XIST expression and permits the continued expression of ...
Cytosine has one other interesting property that none of the other nucleotides have, is that very often in the cell, cytosine can have an extra chemical attached to them, a methyl group. And this DNA methylation at cytosines is thought helps ...
 See also: Methylation, DNA, Sequence, Trans, Gene
|
