Double heterozygote: An individual who is heterozygous at two loci under investigation.
The term proposed by Haldane (1941), by analogy with chemical isomerism, to describe a double heterozygote in coupling phase, that is, with the two dominant factors derived from one parent and the two recessives from the other.
Complementation The ability of two different mutations to produce a wild type phenotype in a double heterozygote. This gives a very strong indication that they do not both affect the same gene (cases of intragenic complementation are very rare).
 See also: Express, Recessive, Biology, Trans, Organ
  
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