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Elongation factor

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elongation factor
One of a group of nonribosomal proteins required for continued translation of mRNA following initiation. (Figure 4-39) ...


Savelsbergh A, Katunin VI, Mohr D, Peske F, Rodnina MV, Wintermeyer W: An elongation factor G-induced ribosome rearrangement precedes tRNA-mRNA translocation.
Wilson DN, Nierhaus KH: The ribosome through the looking glass. ...

Elongation factor
A protein that facilitates protein synthesis.
Endonuclease
An enzyme that makes breaks in a molecule of DNA by hydrolyzing internal phosphodiester bonds.

Elongation factor - GTP-dependent proteins that help bring aa-tRNA to the acceptor site of a ribosome during translation. Elongation factors also help in the translocation process. Energy is supplied by the hydrolysis of GTP to GDP.

an elongation factor (called EF-Tu in bacteria)
GTP (the source of the needed energy) ...

EF Elongation factor; elongation factors are proteins facilitating translational elongation.
efferent /EF-er-rənt/ Leading or carrying away.

During translation elongation, tRNA first binds to the ribosome as part of a complex with elongation factor Tu (EF-Tu) or its eukaryotic (eEF-1) or archaeal counterpart. This initial tRNA binding site is called the A/T site.

The aminoacyl-tRNA is brought to the ribosome through a series of interactions with EF-Tu (an elongation factor).

During codon recognition, an elongation factor assists hydrogen bonding between the mRNA codon under the A site with the corresponding anticodon of tRNA carrying the appropriate amino acid.
This step requires the hydrolysis of two GTP.

Elongation factor (← links)
Transformant (← links)
Rna polymerases (← links)
Mesokaryotic (← links)
Codon initiator (← links)
Purples (← links)
Clone cells (← links)
Ribosome (← links)
Heat-shock proteins (← links) ...

A molecule of water is released ( it is a condensation reaction) (Diagram 3b). This only happens after hydrolysis of a GTP into GDP which allows the elongation factor to leave.

and translation - the two central processes in molecular biology - do not show the typical bacterial features, but are extremely similar to those of eukaryotes. For instance, archaean translation uses eukaryotic initiation and elongation factors, ...

of the cytoplasm but it also requires of course that messenger RNA that's the guide for the ribosomes as well as other helping molecules called t-RNa for transfer RNA and other factors sometimes they're called initiation factors or elongation factors ...

See also: See also: Trans, Protein, Proteins, Sequence, Translation

Biology  Elements  Embryo

 
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