Epigenetics is a term in biology used today to refer to features such as chromatin and DNA modifications that are stable over rounds of cell division but do not involve changes in the underlying DNA sequence of the organism.
Epigenetics and Inheritance
We used to think that a new embryo's epigenome was completely erased and rebuilt from scratch. But this isn't completely true. Some epigenetic tags remain in place as genetic information passes from generation to generation, a process called epigenetic inheritance.
Epigenetics refers to modifications in gene expression that are controlled by heritable but potentially reversible changes in DNA methylation and/or chromatin structure.
(Date:3/29/2011)... 2011)A new interventional radiology treatment that blocks ... shows comparable clinical results to transurethral resection ... gold standard (or most common) treatment. However, ... of the risks associated with TURP, such ...
Epigenetic engineering and the art of epigenetic manipulation
Author Affiliations ...
The inheritance of a particular trait that is not encoded in the nucleotide sequence.
~. Inherited changes in gene expression resulting from altered chromatin structure or DNA modification (usually methylation) rather than from changes in DNA sequence.
~s: The study of heritable changes in gene expression that occur without a change in DNA sequence. ~ phenomena such as imprinting and paramutation violate Mendelian principles of heredity.
Another place where developmental biology has led to the questioning of tenets of the modern evolutionary synthesis is the field of ~s, the study of how environmental factors affect the way genes express themselves during development.
Relating to, or produced by the chain of developmental processes in epigenesis that lead from genotype to phenotype after the initial action of the genes.
~ mechanisms can contribute to regulation of gene expression in hybrids, either directly or by releasing repression on silenced heterochromatic elements, which can then influence neighboring genes.
~s Study of the relationship between genotype and phenotype as mediated by developmental processes.
epigynous Floral parts (sepals, petals, and stamens) appear to arise from the top of an ovary; the ovary is said to be inferior.
~ change — A modification of a chromosome that does not alter the base sequence, but alters the expression of a gene. ~ changes may be stable in an individual, but may be reversed during gametogenesis or early development.
This regulation is often the result of ~ changes in chromatin, such as the acetylation of histones or the methylation of DNA.
One of the things that is recently been adapting a lot of modern understanding of genetics and inheritance is this idea of ~s.
These are often referred to as ~ inheritance and may include phenomenon such as DNA methylation, prions, and structural inheritance.
Changes in genotype, as well as ~ factors, can lead to changes in phenotype, the appearance or behavior of an organism. An organism's phenotype can have dramatic effects on its reproductive success, that is, how many viable offspring it produces.
Mutations and inherited variation ...
have an interesting description of differentiation: "Cell fate is governed not only by the genome, but also by chemical changes to DNA and its associated proteins, a research field called ~s.
Moreover, there are many other things involved in development: ~ factors (para-genetic inheritance and environmental modulation of genetic effects), cytological inheritance (organelles, cell membranes, ribosomes and enzymes from parent cells, and parent organisms).
DNA methylation plays a role in normal organismal development and cellular differentiation in multicellular organisms. Many methylation modifications affecting gene expression are heritable, regulation of this sort is called "~." ...
See also: What is the meaning of Biology, Express, Trans, Gene, DNA?