Epistatic interaction: In genetic epidemiology, an epistatic effect is the modification of the risk conferred by one marker by the presence of a marker from an unrelated gene (unlinked gene-gene interaction).
Epistatic
A gene which suppresses the expression of another gene (= the hypostatic gene) when the two are not alternate alleles. See epistasis.
Related Terms:
Gene expression ...
Two-locus epistatic interactions can be either synergistic (enhancing the effectiveness) or antagonistic (reducing the activity).
Gene 1 is then said to be epistatic to gene 2. Okay, that also sounds kind of complicated. Let me give you an example. If you look at the color of animals...
A gene is said to be epistatic when its presence suppresses the effect of a gene at another locus. Epistatic genes are sometimes called inhibiting genes because of their effect on other genes which are described as hypostatic.
pink flower color is epistatic to red flower color.
B.
pink flowers are the result of a blending of the red and white genotypes.
After the results are graphed, epistatic interactions are identified. According to Thomas Cheesbrough, (South Dakota State University, Brookings), ...
This ratio is 9:7 instead of the 9:3:3:1 one would expect of a dihybrid cross between heterozygotes. Of the two genes (C and P), when either is homozygous recessive (cc or pp) that gene is epistatic to (or hides) the other.
 See also: Gene, Express, Organ, Allele, Expression
  
|
RSS
