exons whose sequence encodes the polypeptide;
introns that will be removed from the mRNA before it is translated [Discussion];
a transcription start site
a promoter ...
Exons and "The Curly Shuffle"
I've mentioned the term exon shuffling in several of my posts, so I might as well get around to explaining what the hell I'm talking about.
Exons Regions of pre-mrna that are retained in mature mrna.
Exonuclease An enzyme that digests nucleic acids from the ends of the molecule, rather than at an internal site; ...
Exons are that part of the RNA that code for proteins. Now, RNA, when it first gets transcribed, is a very, very long piece of RNA molecule. And really, the important parts of that RNA are the exons.
Exons can also be identified by procedures in which a genomic fragment is cloned into an intron of a mammalian expression vector. A fragment containing an exon will be included in the mRNA expressed from the vector.
exons
The Biology Project
University of Arizona
Thursday, October 24, 1996
Contact the Development Team ...
Exons: The protein- coding DNA sequences of a gene. Compare introns.
Exonuclease: An enzyme that cleaves nucleotides sequentially from free ends of a linear nucleic acid substrate.
Some of the exons will be wholly or part of the 5' untranslated region (5' UTR) or the 3' untranslated region (3' UTR) of each transcript.
The inclusion or exclusion of different exons to form different mRNA transcripts. (See RNA.) Amino acid. Any of 20 basic building blocks of proteins-- composed of a free amino (NH2) end, a free carboxyl (COOH) end, and a side group (R).
Exons -- portion of a gene included in the transcript of a gene and survives processing of the RNA in the cell nucleus to become part of a spliced messenger of a structural RNA in the cell cytoplasm; ...
In this case, different sets of promoters can be spliced with certain sets of other exons.
Eukaryotic DNA contains both exons (coding sequences) and introns (intervening sequences). In eukaryotic cells this DNA is used as a template for the production of mRNA, which must then undergo mRNA splicing.
RNase protection assay: This is a sensitive method to determine (1) the amount of a specific mRNA present in a complex mixture of mRNA and/or (2) the sizes of exons which comprise the mRNA of interest.
Introns are cut out of the message and the exons are spliced together before the mRNA leaves the nucleus. There are several examples of identical messages being processed by different methods, often turning introns into exons and vice-versa.
The gene for hemophilia is 186,000 base pairs, and has 26 exons separated by 25 introns. Mutations in the gene can be detected by RFLPs.
A process by which introns are removed from primary See RNA transcripts leaving only exons that encode the amino acid sequence of a protein.
Related Terms:
Intron ...
The hypothesis put forward by Walter Gilbert that exons code for functional units of a protein and that evolution of new genes has proceeded by recombination or exclusion of exons.
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z ...
The DNA sequence of a gene annotated with sites of regulatory elements, introns, exons and mutations.
Related Terms:
Mutation
The term which De Vries introduced into biological literature for an abrupt change of genotype which is inherited.
Mature transcript of RNA splicing which removes introns and joins exons in the primary transcript. mRNA usually has a 5' UTR, 3' UTR and polyA.
Related
3' UTR 5' UTR Mature transcript Primary transcript Splicing cis-splicing polyA trans-splicing ...
The remaining portions of mRNA are called exons. They are spliced together to form a mature mRNA transcript.
The Nucleus
DNA is located in an organelle called the nucleus.
any non-intron section of the coding sequence of a gene; together, the exons constitute the mRNA and are translated into protein
Source: Jenkins, John B. 1990. Human Genetics, 2nd Edition. New York: Harper & Row
...
intron An intervening or noncoding segment of a gene; introns separate exons.
introvert A tubular, eversible extension of the head, bearing the mouth at its tip.
invagination An infolding of a layer of tissue to form a sac-like structure.
In alternative splicing, the same pre-mRNA molecule, which consists of introns and exons, is spliced in different ways to produce mature mRNAs of different lengths and different functionality.
altruistic behavior ...
Different ways of combining a gene's exons to make variants of the complete protein
Amino acid ...
Alternative mRNA splicing. The inclusion or exclusion of different exons to form different mRNA transcripts. (See RNA.) ...
exon - segment of DNA sequence in a gene that will be transcribed in the nucleus, spliced to other exons, and transported to the cytoplasm as a part of the mature mRNA; see also intron.
A region of a gene that is present in the final functional transcript (mRNA) from that gene. Any non-intron section of the coding sequence of a gene; together the exons constitute the mRNA and are translated into protein.
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Ab initio gene prediction: A computing biology technique that attempts to identify genes without any knowledge of their function nor of the genetics of the organism. This can be accomplished because different gene features, such as exons, introns, ...
(genetics) a segment of dna that is involved in producing a polypeptide chain; it can include regions preceding and following the coding dna as well as introns between the exons; it is considered a unit of heredity; ...
ExonsThe coding sections of eukarotic genes, separated by introns.
Expression vectorA vector which is designed to allow expression (transcription and translation) of the inserted section of DNA.
generally take the form of associations of data such as genes, to keywords such as GO terms that describe the function, subcellular localization and processes involving the gene product. Structural annotations (e.g. transcription start sites, exons, ...
Compare exons.
Inversion Occurs where a chromosome breaks in two and becomes reattached in reverse orientation. This may or may not affect gene function.
 See also: Trans, Gene, DNA, Sequence, Protein
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