Expression quantitative trait loci (eQTLs) are genomic loci that regulate gene transcription and expression on a genome-wide scale. Some eQTLs are active in all tissue types (known as static eQTLs) while others are tissue-dependent (dynamic).
expressivity
the degree to which a particular genotype is expressed in the phenotype.
Source: Jenkins, John B. 1990. Human Genetics, 2nd Edition. New York: Harper & Row ...
Expressed sequence tag
An expressed sequence tag or EST is a short sub-sequence of a transcribed protein-coding or non-protein coding DNA sequence.
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Definition of expressed :
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Gene Expression
Gene expression is the process by which the information encoded in a gene is used to direct the assembly of a protein molecule. The cell reads the sequence of the gene in groups of three bases.
The expression of genes involved in the inflammatory response is controlled both transcriptionally and post-transcriptionally.
Gene expression in eukaryotes is controlled by a variety of mechanisms that range from those that prevent transcription to those that prevent expression after the protein has been produced.
ESTs, "expressed sequence tags"
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STRPs, "short tandem repeat polymorphisms" ...
Gene Expression.
When genes are expressed, the genetic information (base sequence) on DNA is first transcribed (copied) to a molecule of messenger RNA in a process similar to DNA replication.
Most genes are expressed as proteins. The synthesis within a cell of a particular protein can be detected by antibodies able to bind to that protein.
Heterochromatin tends to be most concentrated along chromosomes at certain regions of the structures, such as the centromeres and telomeres. Genes typically located in euchromatin can be experimentally silenced (not expressed) by relocating them ...
Expressed sequence tag (EST) is STS derived from cDNA.
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Expression vector
A cloning vector designed so that a foreign gene inserted into the vector will be expressed in the host organism. The inserted DNA is often placed under the control of a strong, regulatable promoter (e.g.
Expressed gene: See gene expression.
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FISH (fluorescence in situ hybridization): A physical mapping approach that uses fluorescein tags to detect hybridization of probes with metaphase chromosomes and with the lesscondensed somatic ...
expression In relation to genes, the phenotypic manifestation of a trait. Expression may be age-dependent (e.g., Huntington disease) or affected by environmental factors (e.g., dark fur on Siamese cats).
Expressivity The degree of expression of a mutant phenotype. If there is a variable expressivity it may range from mild symptoms to a severe phenotype. See also penetrance.
expression vector
A vector that allows a DNA sequence cloned into it to be transcribed when the vector is introduced into a cell.
expressivity ...
Express. To translate a gene's message into a molecular product.
Expression library. (See Library.)
F ...
Expressivity: The range of phenotypes resulting from a given genotype (cystic fibrosis, for example, may have a variable degree of severity).
Expressed gene See: gene expression
Expressed sequence tag (EST) A short strand of DNA that is a part of a cDNA molecule and can act as identifier of a gene. Used in locating and mapping genes.
See also: cDNA, sequence tagged site ...
Gene expression: The process by which genes express themselves: in the cell, ge ne expression results in the manufacture of proteins that determine an organism's characteristics.
over expression A DNA construct in which a gene is fused to a promoter conferring a constitutive and or high level of expression.
P1 A plasmid vector derived from Bacteriophage P1 used to clone DNA fragments between 70-95 kb in length.
Expression (β links)
Rev (β links)
Mrna (β links)
Expression gene (β links)
Provirus (β links)
Proviruses (β links)
Genome (β links)
Chromosome (β links)
Chromosomes (β links)
Minus-strand nucleic acid (β links) ...
Expressing eukaryotic genes in bacteria presents other problems. After proteins are assembled in eukaryotic cells they are often modified.
Expression
- The physical manifestation of the information contained in a gene.
EXPRESSION VECTOR - A plasmid or phage designed for production of a polypeptide from inserted foreign DNA under specific controls. Often an inducer is used.
Expression clone: This is a clone (plasmid in a bacteria, or maybe a l phage in bacteria) which is designed to produce a protein from the DNA insert.
Always expressed in an unregulated fashion (when referring to gene control).
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z ...
1. Phenotypic expression more common in males
2. Sons cannot inherit the trait from their fathers, but daughters can.
Sons inherit their Y chromosome from their father.
phenotype The expression that results from an interaction of one or more gene pairs and the environment.
The nasal index expresses the proportion which the width of the anterior nasal aperture bears to the height of the nose, the latter being measured from the nasion to the lower margin of the nasal aperture, thus:
nasal width X 100/nasal height
55 ...
Sigma. Parameter expressing the seawater density: and equal to 1 minus the density of seawater, measured at a given temperature and at a pressure of l atmosphere ...
A normal gene that when mutated or improperly expressed contributes to the development of cancer. (See Oncogene.) Centers of origin. Usually the location in the world where the oldest cultivation of a particular crop has been identified.
Contiguous genes -- genes physically close on a chromosome that when acting together express a phenotype.
One of several regional or continental expressions of a given biome. Function: refers to action, how something works.
Penetrance An "ll or none" reference to clinical expression of a mutant gene.
Phage A virus for which the natural host is a bacterial cell.
Physical map A map of the locations of identifiable landmarks on DNA (e.g.
Has also been used in expression studies. Yeast artificial chromosomes (YACs) are the most commonly used form.
Creationists like Gish (1979) claim that there is some limitation within "basic kinds", without being able to express exactly what basic kinds might be, or why change is restricted within them.
Sometimes people who inherit the gene for a dominant trait may not express it. This is known as incomplete penetrance. Polydactyly (extra fingers and/or toes) is an autosomal dominant trait.
Although a neutrophil can kill this bead-like string of Streptococcus pyogenes, this particular strain of bacteria expresses streptolysin-s on its surface which kills the white cell through necrosis, ...
Coordination of gene expression, protein synthesis, and post-translational events
Interaction of proteins in complex molecular machines
Predicted vs experimentally determined gene function
Evolutionary conservation among organisms ...
model - a simplified representation of a system (which may be expressed in word, diagrammatic or mathematical terms).
A technique to monitor gene expression in thousands of genes. Thousands of probe DNAs are spotted or synthesized on microscope slides. Sample RNAs are labeled with fluorescent dyes.
enhancer - DNA sequence in a gene that influences the gene's expression by increasing or decreasing its rate of RNA synthesis (via effects on binding and transcription of the basal transcription apparatus including RNA Polymerase); ...
Capsaicin receptors Ion channels expressed in nociceptors that open in response to noxious stimuli such as heat, acidity or chemicals such as capsaicin, the chemical responsible for the "hot" taste of spicy food.
Phenotype the organism's expressed traits what it looks like how the genes are expressed
(pheno = show seem appear)
Phenylketonuria a genetic disorder causing inability to digest phenylalanine
(uria = urine) ...
Prion-related protein (PrP): A normal protein, expressed in the nervous system of animals, whose structure when altered (by interaction with altered copies of itself) is the cause of scrapie in sheep, BSE in cattle, ...
pH. A value used to express relative acidity or alkalinity.
phenoxy herbicides. A group of herbicides derived from phenoxy-acetic acid, including 2,4-D, 2,4,5-T, 2,4-DB, MCPA and silvex.
Beak: Colloquial expression for the protruding mouthpart structures of a sucking insect (= proboscis).
Energy Density is the quantity of energy stored in a given system, or in a spatial region expressed per mass or volume units. For example, the liquid Hydrogen has an energy density of 120 MJoules per kilogram.
A second meaning refers to cloning DNA, or the act of creating copies of an individual gene, for expression in a foreign host, which leads to generation of exact replica macromolecules (e.g. DNA, RNA, proteins).
4. How do Buffers Work?
To do this, for each cube size, divide its surface area by its volume. The number obtained can be expressed as a ration. For example, a surface area of 24cm2 divided by a volume of 3 cm3 = 24/3 = 8/1 = 8:1. 7.
Biomass: The amount of living material per unit area or volume; may be expressed as grams of carbon, total dry weight, and so on.
A variety of techniques that molecular biologists use to manipulate DNA molecules to study the expression of a gene. [Talking Glossary]
Recombination ...
differentiation
Divergence in structure and function of cells as they become specialized during a multicellular organism's development; depends on the control of gene expression (cell differentiation).
Ethologists have been particularly concerned with the evolution of behavior and the understanding of behavior in terms of the theory of natural selection. In one sense the first modern ethologist was Charles Darwin, whose book The expression of the ...
 See also: Trans, Gene, Expression, DNA, Organ
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