expressivity the degree to which a particular genotype is expressed in the phenotype. Source: Jenkins, John B. 1990. Human Genetics, 2nd Edition. New York: Harper & Row ...
Expressivity The degree of expression of a mutant phenotype. If there is a variable expressivity it may range from mild symptoms to a severe phenotype. See also penetrance.
expressivity In genetics, the degree to which a particular genotype is expressed in the phenotype of individuals with that genotype. extinct ...
Expressivity: The range of phenotypes resulting from a given genotype (cystic fibrosis, for example, may have a variable degree of severity).
Gene Expressivity: Range of disease severity for a mutation. Severity can vary widely for some diseases, and few specific mutations have been correlated with the severity of their expression in an individual.
Expressivity Term coined by Voigt (1926) for the phenotypic expression of a penetrant gene or genotype differs in type or degree from slight to intermediate to complete.
Is there variable expressivity and/or incomplete penetrance? Is there a clear and accurate legend? Are the symbols used correctly? Are unknown phenotypes indicated?
genes include those that are transcribed into mRNA and then translated into protein and those that are transcribed into RNA but not translated into protein (e.g., transfer and ribosomal RNAs). The degree of expression is called expressivity.
Marfan syndrome is also an example of dominant negative mutation and haploinsufficiency.[4][5] It is associated with variable expressivity. Incomplete penetrance has not been definitively documented.
See also: Express, Gene, Protein, Cell, Expression
 
|