frame-shift mutation A mutation caused by the insertion or deletion of nucleotides (less than three or a number not a multiple of three) resulting in the improper grouping into codons.
Owen White [The Institute for Genomic Research (TIGR)], describing specialized in-house software to help identify frame-shift errors, ...
BACK MUTATION - Reverse the effect of a point or frame-shift mutation that had altered a gene; thus it restores the wild-type phenotype (see REVERTANT).
Frame-shift mutations occur when the reading frame of the gene is shifted by addition or deletion of one or more bases. With the exception of mitochondria, all organisms use the same genetic code.
One reason for the rareness of frame-shifted mutations being inherited is that if the protein being translated is essential for growth under the selective pressures the organism faces, ...
 See also: Protein, Origin, Enzymes, Gene, Deletion
  
|
RSS
