frameshift mutation
a shift in the reading frame during translation, caused by the addition or deletion of bases in a DNA molecule
Source: Jenkins, John B. 1990. Human Genetics, 2nd Edition. New York: Harper & Row ...
Frameshift Mutation
A frameshift mutation is a type of mutation involving the insertion or deletion of a nucleotide in which the number of deleted base pairs is not divisible by three.
Frameshift
A mutation which adds or deletes one or two base pairs (or any non-multiple of 3) from a coding sequence in a molecule of DNA, so that the genetic code is read out-of-phase.
Frameshift
A frameshift mutation is usually severe, producing a completely nonfunctional protein.
frameshift mutation
A mutation occurring when the number of nucleotides inserted or deleted is not a multiple of 3, thus resulting in improper grouping into codons.
free energy ...
Frameshift mutation A mutation which, by deletion or addition of a number of basepairs which is not divisible by three, causes an alteration in the reading frame of a gene.
[edit] Frameshift mutation
Main article: Frameshift mutation
A frameshift mutation is a mutation caused by indels, ie. inserts or deletes a number of nucleotides that is not evenly divisible by three from a DNA sequence.
Frameshift
A mutation in which there is an addition or deletion of one, ...
Frameshift mutation
A mutation that alters the normal triplet reading frame so that codons downstream from the mutation are out of register and not read properly.
Related Terms:
Mutation ...
Frameshift mutation
- A mutation caused by either the insertion or deletion of a number od nucleotide pairs in DNA, the effect of which is a change in the reading frame of codens in an mRNA molecule during the protein synthesis, ...
Frameshifts often create new STOP codons and thus generate nonsense mutations. Perhaps that is just as well as the protein would probably be too garbled anyway to be useful to the cell.
Designed and implemented new methods for detecting potential sequence errors which can be used to "correct" frameshifts, add quality assurance to sequencing operations, and better detect coding regions in low pass sequences such as ESTs.
These enzymes which break down the nylon oligomers appear to have arisen by frameshift mutation from some other gene which codes for a functionally unrelated enzyme. This adaptation has been experimentally duplicated.
Deletion / at least one base is not copied (frameshift)
Substitution / at least one base is copied wrongly
Interferences with normal base pairing (A-T;C-G)
Degenerate code / different triplets can code for same amino acids ...
A mutation that affects the transcription or translation of part of the gene or operon downstream of the mutant site. For example, nonsense mutations, frameshift mutations, and insertion sequence(IS)-induced mutations.
a base pair mutation or a frameshift mutation) will cause the strand to revert to a normal state, not requiring nutrients to grow. If the mutation screened for has in fact occurred dense spots in the colonies will form.
 See also: DNA, Mutation, Trans, Protein, Gene
  
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