frameshift mutation
a shift in the reading frame during translation, caused by the addition or deletion of bases in a DNA molecule
Source: Jenkins, John B. 1990. Human Genetics, 2nd Edition. New York: Harper & Row ...
Frameshift Mutation
A frameshift mutation is a type of mutation involving the insertion or deletion of a nucleotide in which the number of deleted base pairs is not divisible by three.
frameshift mutation
A mutation occurring when the number of nucleotides inserted or deleted is not a multiple of 3, thus resulting in improper grouping into codons.
free energy ...
Frameshift mutation A mutation which, by deletion or addition of a number of basepairs which is not divisible by three, causes an alteration in the reading frame of a gene.
[edit] Frameshift mutation
Main article: Frameshift mutation
A frameshift mutation is a mutation caused by indels, ie. inserts or deletes a number of nucleotides that is not evenly divisible by three from a DNA sequence.
Frameshift mutation
A mutation that alters the normal triplet reading frame so that codons downstream from the mutation are out of register and not read properly.
Related Terms:
Mutation ...
Frameshift mutation
- A mutation caused by either the insertion or deletion of a number od nucleotide pairs in DNA, the effect of which is a change in the reading frame of codens in an mRNA molecule during the protein synthesis, ...
A frameshift mutation is usually severe, producing a completely nonfunctional protein.
These enzymes which break down the nylon oligomers appear to have arisen by frameshift mutation from some other gene which codes for a functionally unrelated enzyme. This adaptation has been experimentally duplicated.
For example, a +1 frameshift mutation located a short distance downstream from a -1 frameshift mutation can restore the reading frame of a protein and thereby allow production of a functional product.
A mutation that affects the transcription or translation of part of the gene or operon downstream of the mutant site. For example, nonsense mutations, frameshift mutations, and insertion sequence(IS)-induced mutations.
The 16 September 1999 issue of The New England Journal of Medicine reports the results of a year-long trial of recombinant human leptin in a 9-year-old girl who is homozygous for a frameshift mutation in her leptin genes. The findings: ...
a base pair mutation or a frameshift mutation) will cause the strand to revert to a normal state, not requiring nutrients to grow. If the mutation screened for has in fact occurred dense spots in the colonies will form.
containing from 1 to 5 X chromosomes: 45, X; 46, XX; 47, XXX; 48, XXXX; and 49, XXXXX. An additional one, 49, XYYYY, is also available.
Patients with characterized BRCA1 gene mutations (including missense, nonsense, and frameshift mutations) and ...
 See also: Frameshift, DNA, Mutation, Trans, Sequence
  
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