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Frameshift mutations

Biology Frameshift MutationFree energy

Mutations that disrupt the reading frame by insertions or deletions of a non-multiple of 3 nucleotide bases are known as frameshift mutations.

 


Pseudogene
An inactive gene derived from an ancestral active gene. Pseudogenes are often recognized by nonsense or frameshift mutations that disrupt an open reading frame that encodes a functional protein in a related genome.

Chain termination mutation A mutation which leads to the premature termination of the polypeptide chain specified by the mutant gene. Nonsense mutations, frameshift mutations and splice junction mutations can all give rise to premature chain ...

A mutation that affects the transcription or translation of part of the gene or operon downstream of the mutant site. For example, nonsense mutations, frameshift mutations, and insertion sequence(IS)-induced mutations.

containing from 1 to 5 X chromosomes: 45, X; 46, XX; 47, XXX; 48, XXXX; and 49, XXXXX. An additional one, 49, XYYYY, is also available.
Patients with characterized BRCA1 gene mutations (including missense, nonsense, and frameshift mutations) and ...

Some data indicates that there are a suite of related phenomena, for directed mutations have been claimed to: fix single base substitutions, fix frameshift mutations and correct large insertion mutations.

See also: Frameshift Mutation, Gene, Frameshift, Cell, Trans

Biology Frameshift MutationFree energy

 
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