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Gaucher disease (mutations in the GBA gene), Crohn's disease (mutation of NOD2) and familial hypertrophic cardiomyopathy (mutations in CMH1, CMH2, CMH3 and CMH4) are all examples of negative selection.
Genetic bit analysis (GBA)
Technique to score single nucleotide polymorphisms among alleles. It relies on the polymersae chain reaction and enzyme-linked colorimetry to distinguish differences among genotypes.
Related Terms: ...
 See also: Allele, Nucleotide, Locus, SNP, Organ
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