Home (Gene silencing)
Home  
 
 
Home » Biology » Gene silencing


 

Gene silencing

Biology Gene regulatory networkGene splicing

[edit] Gene silencing
The discovery of gene silencing using double stranded RNA, also known as RNA interference (RNAi), ...

 


RNA interference or gene silencing may be a new way to treat Huntington's. Short pieces of double-stranded RNA (short, interfering RNAs or siRNAs) are used by cells to degrade RNA of a particular sequence.

This gene silencing acts in much the same manner as mutation or deletion of one copy of a gene, except that it is not a permanent, heritable change.

This includes phenomena such as X chromosome inactivation in mammalian females, and gene silencing within an organism.
The study of heritable changes in gene function that occur without a change in the sequence of nuclear DNA.

In plants, the gene silencing spreads to adjacent cells (through plasmodesmata) and even to other parts of the plant (through the phloem). RNAi within a cell can continue after mitosis in the progeny of that cell. Triggering of RNAi in C.

See also: DNA, Gene, Protein, Human, Trans

Biology Gene regulatory networkGene splicing

 
 rssRSS