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Gyrase

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DNA gyrase
A topoisomerase that removes supercoils from DNA by first producing double-strand breaks and then sealing them.

 


DNA gyrase A topoisomerase that catalyzes the ATP-driven introduction of negative supercoils into DNA. Also called topoisomerase II.

Gyrase
(Date:3/28/2011)... have completed the first human randomized controlled trial ... uses a catheter-based probe inserted into the renal ... nerves near the kidneys (or in the renal ... The researchers say these results confirm that RDN ...

DNA gyrase
- The protein responsible for relaxing the tension on the double helix owing to supercoiled twists brought about by the unwinding of the double helix without rotation; also called helix-unwinding protein
DNA ligase ...

Some bacteria do this by modifying their DNA gyrase.
Others, e.g., Mycobacterium tuberculosis, develop quinolone resistance by synthesizing a protein that resembles a short length of DNA.

Host DNA gyrase puts negative supercoils in the circular chromosome, causing A-T rich regions to unwind and drive transcription.
Transcription starts from the constitutive PL, PR and PR' promoters producing the 'immediate early' transcripts.

See also: Molecule, Trans, Strand, DNA, Polymerase

Biology GynoeciumHabitat

 
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