Haplotypes
Haplotype is a contraction for haploid genotype.
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Definition of haplotype : ...
Haplotype
A haplotype is a set of DNA variations, or polymorphisms, that tend to be inherited together. A haplotype can refer to a combination of alleles or to a set of single nucleotide polymorphisms (SNPs) found on the same chromosome.
Haplotype A set of closely linked alleles which are inherited together.
Hardy-Weinberg law A rule which relates the frequencies of genotypes at a locus in a population to the frequencies of the alleles at that locus.
Haplotype A way of denoting the collective genotype of a number of closely linked loci on a chromosome.
Hemizygous Having only one copy of a particular gene. For example, in humans, males are hemizygous for genes found on the Y chromosome.
Haplotype
A set of closely linked genetic markers present on one chromosome which tend to be inherited together (not easily separable by recombination). Some haplotypes may be in linkage disequilibrium.
Related Terms:
Linkage ...
Haplotypes
A brief description of the concept of a haplotype.
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In a molecular systematic analysis, the haplotypes are determined for a defined area of genetic material; ...
Haplotype analysis of 192 Caucasian chromosomes revealed strong linkage disequilibrium between CCR5 and two microsatellite loci.
When the observed frequencies of haplotypes in a population does not agree with haplotype frequencies predicted by multiplying together the frequency of individual genetic markers in each haplotype.
The large number of alleles involved mean no two individuals, even in a family, will have the same identical haplotype. Identical twins have a 100% HLA match. The best matches are going to occur within a family.
Although the HGP has been completed, SNP studies continue in the International HapMap Project, whose goal is to identify patterns of SNP groups (called haplotypes, or "haps").
This methodology has several applications, such as amplifying certain haplotypes (when certain alleles at 2 or more SNPs occur together on the same chromosome [Linkage Disequilibrium]) or detection of recombinant chromosomes and the study of meiotic ...
 See also: DNA, Chromosome, Sequence, Genome, Organ
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