Histone

histone
a type of basic protein associated with DNA in chromosomes
Source: Jenkins, John B. 1990. Human Genetics, 2nd Edition. New York: Harper & Row ...

Histones
proteins that dna tightly coils around to form chromosomes.
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Histone
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Histone
In biology, histones are the chief proteins of chromatin. They act as spools around which DNA winds and they play a role in gene regulation. Histones are found in the nuclei of eukaryotic cells.

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Histone
A histone is a protein that provides structural support to a chromosome. In order for very long DNA molecules to fit into the cell nucleus, they wrap around complexes of histone proteins, giving the chromosome a more compact shape.

The protein remaining in chromatin after the histones are removed. The scaffold structure is made of nonhistone proteins.
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Histone Modifications
Although their amino acid sequence (primary structure) is unvarying, individual histone molecules do vary in structure as a result of chemical modifications that occur later to individual amino acids.
These include adding: ...

Histone
A basic protein from eukaryotes (or Archae) which binds to DNA, forming nucleosomes, and packaging the DNA into chromatin.
Histone-like proteins
Proteins from bacteria which bind to DNA, and compact the DNA.

histones -- proteins attached to the DNA of eukaryotes which allows it to be packaged into chromosomes.

histone proteins Proteins associated with DNA in eukaryote chromosomes.
homeobox genes Pattern genes that establish the body plan and position of organs in response to gradients of regulatory molecules.

histone
(hiss-tone)
A small protein with a high proportion of positively charged amino acids that binds to the negatively charged DNA and plays a key role in its chromatin structure.
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Histones Very basic proteins which bind tightly to the acidic DNA to form a nucleosome - the basic building block of chromatin. They are highly conserved throughout eukaryotic evolution.

histones - basic proteins that bind and "package" eukaryotic DNA; major protein constituent of chromosomes.

Histone acetyltransferase (HAT) An enzyme that catalyzes the attachment of acetyl groups from acetyl coa to specific lysine residues in the amino-terminal domains of histones.

Histone
Protein associated with DNA in chromosomes in the nucleus of the cell.
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Histone
- Basic protein complexed with DNA in the chromosomes of eukaryotes
Homolog ...

histones
Five kinds of proteins forming complexes with Eukaryotic DNA.
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histone Any of several simple proteins found in cell nuclei and complexed at one time or another with DNA. Histones yield a high proportion of basic amino acids on hydrolysis; characteristic of eukaryotes.

A single DNA molecule, a tightly coiled strant of DNA, condensed into a compact structure in vivo by complexing with accessory histones or histone-like proteins. Chromosomes exist in pairs in higher eukaryotes.

Each DNA strand wraps around groups of small protein molecules called histones, forming a series of bead-like structures, called nucleosomes, connected by the DNA strand (as illustrated in Figure 1).

The proteins associated with DNA are collectively known as histones. They are relatively short polypeptides which are positively charged (basic) and thus are attracted to the negatively charged (acidic) DNA.

In 19951996 we continued to map and identify nonhistone proteins binding at loci along the yeast chromosome.

The histones are also synthesized since the new DNA must wrap itself around the histones immediately. What began as one chromosome composed of a single double-stranded DNA, becomes two chromatids each with a single double-stranded DNA molecule.

A chromosome is an organized structure consisting of DNA and histones. The set of chromosomes in a cell and any other hereditary information found in the mitochondria, chloroplasts, or other locations is collectively known as its genome.

Chromatin: The complex of DNA and associated histone and non-histone proteins that represents the normal state of genes in the nucleus.

When DNA condenses, the molecule becomes wrapped around proteins called histones. The histones are then arranged in a coiled pattern to produce a larger fiber. This larger fiber is further compacted by looping to produce looped domains.

Chromosome organized in nucleosomes composed of histones and other protein factors.
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Chromosome ...

The protein of interest could for example be a transcription factor, or a specific modified histone, or any other DNA binding protein. This procedure requires an antibody to that protein of interest.

See also: Protein, DNA, Proteins, Chromosome, Trans