Homologous Recombination
Homologous recombination is a type of genetic recombination that occurs during meiosis (the formation of egg and sperm cells).
Homologous recombination
The physical exchange of DNA between two homologous DNA molecules. Requires the RecA protein in enteric bacteria. Also called general recombination.
Homologous recombination: Rearrangement of related DNA sequences on a different molecule by crossing over in a region of identical sequence.
Homologous Recombination. Here the broken ends are repaired using the information on the intact ...
homologous recombination - process whereby stretch of DNA in a chromosome is replaced by a homologous (highly similar) DNA molecule for the purpose of altering the gene's function.
Homologous recombination. The exchange of DNA fragments between two DNA molecules or chromatids of paired chromosomes (during crossing over) at the site of identical nucleotide sequences.
Homologous recombination Swapping of DNA fragments between paired chromosomes.
Homology Similarity in DNA or protein sequences between individuals of the same species or among different species.
Homologous recombination Recombination between homologous segments of two DNA molecules. Also called general recombination.
Homologs Molecules that have evolved from a common ancestor. Also referred to as homologous molecules.
Homologous Recombination is the process by which two chromosomes, paired up during prophase 1 of meiosis, exchange some distal portion of their DNA.
Homologous recombination
Substitution of a segment of DNA by another that is identical (homologous) or nearly so. Occurs naturally during meiotic recombination; also used in the laboratory for gene targeting to modify the sequence of a gene.
6.1 DNA: Homologous recombination.
Two double helices exchange homologous regions, usually so that a non-homologous region farther down can be inserted. This method can be used for insertion of viral DNA into a host cell's genome.
Gene disruption by homologous recombination
Knockout technology, as well as other genetic engineering approaches, depends on the ability to target genes for insertion into particular locations within the host chromosome.
Method for the introduction of genetic modifications into specific genes by homologous recombination using Cre a site-specific, bacteriophage P1-derived recombinase. The Cre recombinase cuts at the loxP-tagged genes.
This laborious method involves transfecting a crippled gene into cultured embryonic stem cells, searching through the thousands of resulting clones for one in which the crippled gene exactly replaced the normal one (by homologous recombination), ...
Recombination may come about through random orientation of non-homologous chromosome pairs on the meiotic spindles, from crossing-over between homologous chromosomes, from gene conversion, or by other means. See homologous recombination.
 See also: Recombination, DNA, Chromosome, Sequence, Gene
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