hybridoma
a hybrid cell made from the fusion of a cancer cell with a lymphocyte that has been induced to produce antibodies
Source: Jenkins, John B. 1990. Human Genetics, 2nd Edition. New York: Harper & Row ...
Hybridoma
B-lymphocytes are fused with tumour cells in laboratory cultures
They divide rapidly to form a clone of identical cells
Specific monoclonal antibodies are continuously produced and useful as ...
Hybridoma. A hybrid cell, composed of a B Iymphocyte fused to a tumor cell, which grows indefinitely in tissue culture and is selected for the secretion of a specific antibody of interest.
Hybridoma cell A cell, resulting from the fusion of an antibody-producing cell and a tumor cell, that produces a single antibody and has an unlimited capacity for proliferation.
[edit] Hybridoma Cell Production
Monoclonal antibodies are made by fusing the spleen cells from a mouse that has been immunized with the desired antigen with myeloma cells.
Hybridoma
- A type of hybrid cell produced by fusing a normal cell with a tumor cell.
Hybridoma cultures can be maintained indefinitely:
in vitro; that is, in culture vessels. The yield runs from 10-60 µg/ml.
in vivo; i.e., growing in mice. Here the antibody concentration in the serum and other body fluids can reach 1-10 mg/ml.
hybridoma Fused product of a normal and a myeloma (cancer) cell, which has some of the characteristics of the normal cell.
hydatid cyst A type of cyst formed by juveniles of certain tapeworms (Echinococcus) in their vertebrate hosts.
The fused hybrid cells (called hybridomas) will multiply rapidly and indefinitely (since they are cancer cells after all) and will produce large amounts of antibodies.
ATCC offers over 3000 well-characterized cell lines and hybridomas through five different government-sponsored collections, thus providing a valuable resource for studying gene expression.
 See also: Hybrid, Human, Cell, Cells, Trans
  
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