Insertion mutations. Changes in the base sequence of a DNA molecule resulting from the random integration of DNA from another source. See DNA, Mutation. In situ. Refers to performing assays or manipulations with intact tissues.
Some data indicates that there are a suite of related phenomena, for directed mutations have been claimed to: fix single base substitutions, fix frameshift mutations and correct large insertion mutations.
These arrays can be used effectively for comparison sequencing with APEX and for analysis of gene expression with mRNA templates and reverse transcriptase. Substitution, deletion, and insertion mutations have been detected.
See also: Mutation, Trans, Trait, Strand, Express
 
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