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Intermediate filament

Biology InterkinesisIntermembrane space

Intermediate filaments (IFs) are cytoskeletal structures formed by members of a family of related proteins. Intermediate filaments have a diameter between that of actin (microfilaments) and microtubules.

 


Intermediate filaments are one component of the cytoskeleton - important structural components of living cells. Their size is intermediate between that of microfilaments and microtubules. They are assembled from several different proteins.

Intermediate filaments
cytoplasmic filaments intermediate in diameter (about 10 nanometers) between the microfilaments and the microtubules. They may be composed of any of a number of different proteins and form a ring around the cell nucleus.

Intermediate Filaments
Intermediate filaments are a very broad class of fibrous proteins that play an important role as both structural and functional elements of the cytoskeleton.

Intermediate Filaments
These cytoplasmic fibers average 10 nm in diameter (and thus are "intermediate" in size between actin filaments (8 nm) and microtubules (25 nm)(as well as of the thick filaments of skeletal muscle fibers).

intermediate filament
A component of the cytoskeleton that includes all filaments intermediate in size between microtubules and microfilaments.
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Intermediate Filaments
Intermediate filaments are composed of long, threadlike protein molecules wrapped around one another like the strands of a cable.

Intermediate filaments Filaments ranging from approximately 7 to10 nm in diameter that can be components of the cell cytoskeleton in epithelial cells; keratins are intermediate filaments.

Intermediate filaments are another cytoskeletal protein component. As their name implies they are intermediate in size between the larger microtubules and the smaller microfilaments. They form parts of some tight junctions between cells.

intermediate filament The chemically heterogeneous group of protein fibers, the specific proteins of which can vary with cell type. One of the three most prominent types of cytoskeletal filaments.

Intermediate filaments are between eight and eleven nm in diameter. They are between actin filaments and microtubules in size. The intermediate fibers are rope-like assemblies of fibrous polypeptides.

Examples include insulin, estrogen, and testosterone.

Intermediate filament Part of the cytoskeleton that provides strength. Some intermediate filaments form nails, hair, and the outer layer of skin. Others are found in nerves or other organs.

The primary types of fibers comprising the cytoskeleton are microfilaments, microtubules, and intermediate filaments.
Microfilaments
Microfilaments are fine, thread-like protein fibers, 3-6 nm in diameter.

A combination of western and Southern blots allows us to conclude that a protein with a molecular weight of about 80 kD and some similarity to the intermediate filaments is responsible for the MA/NM interaction.

See also: Protein, Proteins, Cell, Cells, Organ