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Intragenic

Biology IntestineIntrogression

Intragenic suppressor
Restoration of partial or complete wild-type phenotype by second mutation in the same gene as a primary mutation which resulted in a negative phenotype.

 


Intragenic
Within a gene; cf intergenic
Related Terms:
Gene family
Groups of closely related genes that make similar products.

Intragenic
Within a gene; cf intergenic
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We have examined in detail methods for optimizing queries such as "retrieve all known human sequence containing an Alu repeat in an intragenic region" where the data sources are heterogeneous and distributed across the Internet.

Intragenic complementation, allelic complementation, or interallelic complementation - two mutations map to the same locus, yet the two alleles complement in the heteroallelic diploid. Causes of intragenic complementation include: ...

allele that is functionally but not structurally allelic, that is wild-type recombinants can be recovered by intragenic recombination from heterozygotes containing two different pseudoalleles.
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Complementation The ability of two different mutations to produce a wild type phenotype in a double heterozygote. This gives a very strong indication that they do not both affect the same gene (cases of intragenic complementation are very rare).

See also: Gene, Mutation, Express, Chromosome, Sequence

Biology IntestineIntrogression

 
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