Notice that the alleles for the three different loci do not overlap. The lower panel shows the alleles for Bob Blackett's mother Norma for the D3S1358, vWA, and FGA loci.
Expression quantitative trait loci (eQTLs) are genomic loci that regulate gene transcription and expression on a genome-wide scale. Some eQTLs are active in all tissue types (known as static eQTLs) while others are tissue-dependent (dynamic).
Locus (loci)
The position on a chromosome where a particular genetic trait resides. Sometimes used to describe multiple genes that affect the same function.
Disease Loci
In the past 2 years, at least five major disease genes have been mapped to chromosome 2, including those for induced Waardenberg syndrome (WSI, described below), holoprosencephaly, ...
Loci
Plural of locus.
Related Terms:
Locus
The position of a gene on a chromosome or other chromosome markers; also, the DNA at that position. The use of the term locus is sometimes restricted to main regions of DNA that are expressed.
all loci on the same chromosome
Source: Jenkins, John B. 1990. Human Genetics, 2nd Edition. New York: Harper & Row
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The S loci are (as in SSI plants) extremely polymorphic; that is, there is an abundance of multiple alleles in the population.
Incompatibility is controlled by the single S allele in the haploid pollen grain.
A specific loci may contain one of several different coding sequences.
e.g. Many genes have slightly different coding sequences between chromosomes
Macrosatellites also show a similar sequence diversity ...
Locus (pl. loci): The position on a chromosome of a gene or other chromosome marker; also, the DNA at that position. The use of locus is sometimes restricted to mean regions of DNA that are expressed. See gene expression.
M
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noun, plural: loci
1. (general) a place, space or locality, especially a centre of an activity
2. (mathematics) the set of all points whose coordinates satisfy a given equation or condition ...
Example: 3 loci (polygenic)
Height (tallness) in humans is polygenic but the mechanism of gene function or the number of genes involved is unknown.
Suppose that there are 3 loci with 2 alleles per locus (A, a, B, b, C, c).
locus (pl. loci)
a particular place along the length of a certain chromosome where a given gene is located.
log (logarithmic) phase
The exponential phase of growth in a bacterial culture.
the two mutable loci originally identified by Barbara McClintock that were able to move in the genome.
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z ...
locus pl. loci
(loh-kus) [L. place]
A particular place along the length of a certain chromosome where a given gene is located.
logistic population growth ...
Locus (plural = loci). A specific location or site on a chromosome.
Log phase. See Logarithmic phase.
Quantitative trait loci
Quaternary structure
(Date:3/28/2011)... have completed the first human randomized controlled trial ... uses a catheter-based probe inserted into the renal ... nerves near the kidneys (or in the renal ...
Quantitative trait loci (QTL)
The location of a gene that affects a trait that is measured on a quantitative (linear) scale. These traits are typically affected by more than one gene, and also by the environment.
Distances are established by linkage analysis, which determines the frequency at which two gene loci become separated during chromosomal recombination. (See Mapping.) Genetic marker.
Homozygote -- having identical alleles at one or more loci in homologous chromosome segments. Housekeeping genes -- those genes expressed in all cells because they provide functions needed for sustenance of all cell types.
Heterozygosity The presence of different alleles at one or more loci on homologous chromosomes.
Homeobox A short stretch of nucleotides whose base sequence is virtually identical in all the genes that contain it.
At 45 percent of loci in plants there is more than one allele in the gene pool. [allele: alternate version of a gene (created by mutation)] Any given plant is likely to be heterozygous at about 15 percent of its loci.
One case of this phenomenon occurs at loci at the major histocompatibility complex (MHC) wherein some human alleles are much more closely related to some chimpanzee alleles than they are to other human alleles (Fig. 7).
If we use height as an example, we can say it is controlled by additive genes at four different loci.
Distance between two loci. Recombination can be used to determine map distance between two loci. A map distance of 1 centiMogan (cM) is equivalent to the recombination rate of 1%.
This usually occurs at loci such as immunoglobulin or T cell receptor (TCR) genes where a functional rearrangement among genes takes place. One of the alleles is either non-functionally or incompletely rearranged and not expressed.
quantitative trait A genetic trait that is determined by multiple interacting loci, and for which there is a range of phenotypes between phenotypic extremes.
quark A subatomic particle found in the nucleus of the atom.
Human beta-globin genes are scattered at five loci on human chromosome 11. These genes are expressed sequentially during development, and are similar with same-length introns in similar positions in each gene.
Genotype The alleles present in an individual at the locus (loci) under consideration. Alternatively, the sum of all the alleles present in a genome.
sequenced locus Sequenced loci include predicted and experimentally verified transcribed regions.
- A measure of the tendency of some genes to be inherited as a group rather than individually because of the proximity of their loci in the chromosome
Lycopene ...
A locus is the specific physical location of a gene or other DNA sequence on a chromosome, like a genetic street address. The plural of locus is "loci".
Narration Transcription ...
Morgan and his coworkers were able to cause new alleles to form by subjecting fruit flies to mutagens (agents of mutation, or mutation generators). Genes are located on specific regions of a certain chromosome, termed the gene locus (plural: loci).
 See also: DNA, Chromosome, Gene, Sequence, Organ
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