Loci

loci locus Definition of loci The location of a specific gene on a chromosome.

Expression quantitative trait loci (eQTLs) are genomic loci that regulate gene transcription and expression on a genome-wide scale. Some eQTLs are active in all tissue types (known as static eQTLs) while others are tissue-dependent (dynamic).

Loci Plural of locus. Related Terms: Locus The position of a gene on a chromosome or other chromosome markers; also, the DNA at that position. The use of the term locus is sometimes restricted to main regions of DNA that are expressed.

loci (genes, fragile sites, DNA segments, and breakpoints); associated symbol; disorder or syndrome name; chromosomal location; Victor McKusick's Mendelian Inheritance in Man (MIM) number; polymorphisms; alleles; allele population/frequency; ...

All loci on one chromosome are said to be syntenic (literally on the same ribbon). Loci may appear to be unlinked by conventional genetic tests for linkage but still be syntenic. A B C D E F G H I J K L M N O P Q R S T U V W X Y Z ...

all loci on the same chromosome Source: Jenkins, John B. 1990. Human Genetics, 2nd Edition. New York: Harper & Row ...

The S loci are (as in SSI plants) extremely polymorphic; that is, there is an abundance of multiple alleles in the population. Incompatibility is controlled by the single S allele in the haploid pollen grain. Full article ...

locus pl. loci (loh-kus) [L. place] A particular place along the length of a certain chromosome where a given gene is located. logistic population growth ...

A specific loci may contain one of several different coding sequences. e.g. Many genes have slightly different coding sequences between chromosomes Macrosatellites also show a similar sequence diversity ...

Locus (pl. loci): The position on a chromosome of a gene or other chromosome marker; also, the DNA at that position. The use of locus is sometimes restricted to mean regions of DNA that are expressed. See gene expression. Long(q) and short(p) arms: ...

locus (pl: loci) A site on a chromosome. lod score The logarithm of the odds of linkage between two loci.

Example: 3 loci (polygenic) Height (tallness) in humans is polygenic but the mechanism of gene function or the number of genes involved is unknown. Suppose that there are 3 loci with 2 alleles per locus (A, a, B, b, C, c).

locus (pl. loci) a particular place along the length of a certain chromosome where a given gene is located. log (logarithmic) phase The exponential phase of growth in a bacterial culture.

noun, plural: loci 1. (general) a place, space or locality, especially a centre of an activity 2. (mathematics) the set of all points whose coordinates satisfy a given equation or condition ...

Locus (plural = loci). A specific location or site on a chromosome. Log phase. See Logarithmic phase.

The antibody gene loci are dangerous places for proto-oncogenes to take up residence. Translocation of the proto-oncogene c-myc close to the enhancer of the antibody heavy chain genes also produces cancerous B cells resulting in Burkitt's Lymphoma.

Quantitative trait loci (QTL) The location of a gene that affects a trait that is measured on a quantitative (linear) scale. These traits are typically affected by more than one gene, and also by the environment.

Distances are established by linkage analysis, which determines the frequency at which two gene loci become separated during chromosomal recombination. (See Mapping.) Genetic marker.

Homozygote -- having identical alleles at one or more loci in homologous chromosome segments. Housekeeping genes -- those genes expressed in all cells because they provide functions needed for sustenance of all cell types.

Linkage map A map of the relative positions of genetic loci on a chromosome, determined on the basis of how often the loci are inherited together. Distance is measured in centimorgans (cM).

The word locus (plural loci) is Latin for "place". In biology and evolutionary computation, a locus is the position of a gene (or other significant sequence) on a chromosome. A locus can be occupied by any of the alleles of the gene.

At 45 percent of loci in plants there is more than one allele in the gene pool. [allele: alternate version of a gene (created by mutation)] Any given plant is likely to be heterozygous at about 15 percent of its loci.

One case of this phenomenon occurs at loci at the major histocompatibility complex (MHC) wherein some human alleles are much more closely related to some chimpanzee alleles than they are to other human alleles (Fig. 7).

If we use height as an example, we can say it is controlled by additive genes at four different loci.

Distance between two loci. Recombination can be used to determine map distance between two loci. A map distance of 1 centiMogan (cM) is equivalent to the recombination rate of 1%.

This usually occurs at loci such as immunoglobulin or T cell receptor (TCR) genes where a functional rearrangement among genes takes place. One of the alleles is either non-functionally or incompletely rearranged and not expressed.

quantitative trait A genetic trait that is determined by multiple interacting loci, and for which there is a range of phenotypes between phenotypic extremes. quark A subatomic particle found in the nucleus of the atom.

Three-factor cross A method for determining the genetic map position of three linked loci based upon relative frequency of coinheritance of each locus during a cross between two strains with different allelic forms in each gene.

Human beta-globin genes are scattered at five loci on human chromosome 11. These genes are expressed sequentially during development, and are similar with same-length introns in similar positions in each gene.

Allele: Any of the alternative genes which may occupy corresponding positions (loci) on each chromosome of a pair. A mutation, such as one which may be responsible for genetic disease, is an allele.

Genotype The alleles present in an individual at the locus (loci) under consideration. Alternatively, the sum of all the alleles present in a genome.

sequenced locus Sequenced loci include predicted and experimentally verified transcribed regions.

- A measure of the tendency of some genes to be inherited as a group rather than individually because of the proximity of their loci in the chromosome Lycopene ...

A locus is the specific physical location of a gene or other DNA sequence on a chromosome, like a genetic street address. The plural of locus is "loci". Narration Transcription ...

See also: Chromosome, DNA, Gene, Sequence, Genome