Marker
A marker is a DNA sequence with a known physical location on a chromosome. Markers can help link an inherited disease with the responsible genes. DNA segments close to each other on a chromosome tend to be inherited together.
genetic marker
a single gene trait used to follow the transmission of chromosomes or other traits in a mating
Source: Jenkins, John B. 1990. Human Genetics, 2nd Edition. New York: Harper & Row ...
Genetic marker
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Marker rescue
Repair of a mutational defect by recombination. For example, when a cell is co-infected with a mutant phage that is unable to replicate and a wild-type phage, ...
Marker: An identifiable physical location on a chromosome (e.g., restriction enzyme cutting site, gene) whose inheritance can be monitored.
Marker development for the EPM1 region of human chromosome 21, q22.3
J.A. Warrington, K. O'Connor, S. Hebert, M. Harris, R. Goold, A.E. Lehesjoki, A. de la Chapelle, N. Stone, R. Myers and D.R. Cox ...
GeneticMarker In TAIR, genetic markers are any biological object that is used to distinguish between two or more polymorphic states.
Genetic marker A polymorphic locus which can be used in linkage studies. The polymorphism may be anything to do with the DNA at the locus or its possible product so long as it can be recognised with an appropriate test.
Genetic marker. A gene or group of genes used to "mark" or track the action of microbes.
Genome. The genetic complement contained in the chromosomes of a given organism, usually the haploid chromosome state.
Marker genes, such as genes for antibiotic resistance, are often engineered into plasmids. These marker genes enable researchers to know which bacteria have the plasmids. The antibiotic is added to the media used to grow the bacteria.
Marker gene
- Genes that identify which plants have been successfully transformed.
Microarray ...
Marker genes can be used to determine if the gene has been taken up.
Marker genes must have some distinguishable characteristic.
Marker: Two typical usages:
Molecular weight size marker: a piece of DNA of known size, or a mixture of pieces with known size, used on electrophoresis gels to determine the size of unknown DNA's by comparison.
See: marker
Resolution
Degree of molecular detail on a physical map of DNA, ranging from low to high.
any DNA marker co-inherited with the genetic trait of interest
E.
an exon of the disease gene ...
A PCR based marker such as AFLP ( Amplified Fragment Length Plymorphism) is well ... For AFLP finger prints selective primers are used. ...
Full article ...
Selectable marker: A gene, usually encoding resistance to an antibiotic, added to a vector construct to allow easy selection of cells that contain the construct from the large majority of cells that do not.
(See Selectable marker.) Bacillus. A rod-shaped bacterium. Bacillus thuringiensis (Bt). A bacterium that kills insects; a major component of the microbial pesticide industry. Backcross. Crossing an organism with one of its parent organisms.
Linkage -- analysis of pedigree the tracking of a gene through a family by following the inheritance of a (closely associated) gene or trait and a DNA marker.
One centimorgan is equal to a 1% chance that a marker at one genetic locus will be separated from a marker at a second locus due to crossing over in a single generation.
Selectable markerA gene which is usually constitutively expressed and allows the selection of cells which carry it through growth on a selective medium.
Tumor marker (← links)
Mineralocorticoids (← links)
Allatostatin (← links)
Tissue hormones (← links)
Endocrine hormones (← links)
Tumour marker (← links)
Adrenal gland (← links)
Steroid (← links)
Erdheim tumour (← links) ...
In most NFT-bearing neurons, we observed a strong reduction in acetylated a-tubulin immunoreactivity (a marker of stable microtubules) and a reduction of the in situ hybridization signal for tubulin mRNA.
Gusella and his research team, who used RFLPs to identify a marker. Testing a large library of human DNA fragments, Gusella et al. found the needle in the haystack. The enzyme used was Hind III.
Case 2: Screening for a RFLP "marker"
If a particular RFLP is usually associated with a particular genetic disease, then the presence or absence of that RFLP can be used to counsel people about their risk of developing or transmitting the disease.
Cytotoxic T lymphocytes (CTL) recognize surface markers on othercells in the body that label those cells for destruction. In this way, CTLs help to keep virus-infected or malignant cells in check.
The proximity of two or more markers (e.g. genes, RFLP markers) on a chromosome; the closer together the markers are, the lower the probability that they will be separated during DNA repair or replication processes (binary fission in prokaryotes, ...
Other genetic markers allowed him to identify hybrids. The two varieties were planted in a common field. Any plant's nearest neighbors were always plants of the other strain.
Chromosome walking is a technique to clone a gene (e.g., a disease gene) from its known closest markers. The closest linked marker (e.g., EST or a known gene) to the gene is used to probe a genomic library.
Highly polymorphic DNA marker comprised of mononucleotides, dinucleotides, trinucleotides or tetra-nucleotides that are repeated in tandem arrays and distributed throughout the genome.
Epistatic interaction: In genetic epidemiology, an epistatic effect is the modification of the risk conferred by one marker by the presence of a marker from an unrelated gene (unlinked gene-gene interaction).
A genetic map based on the frequencies of recombination between markers during crossing over of homologous chromosomes. The greater the frequency of recombination between two genetic markers, the farther apart they are assumed to be.
lipid ...
A set of closely linked genetic markers present on one chromosome which tend to be inherited together (not easily separable by recombination). Some haplotypes may be in linkage disequilibrium.
A technique in which DNA restriction fragment length polymorphisms (RFLPs) are used as reference markers for mapping in relation to known genes or other RFLP loci.
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z ...
Bait containing no vaccine but may have biomarker with which to measure uptake ...
When a cell does not display the chemical markers that say "Made in Mike", an immune system response may be triggered. This is the basis for immunity, allergies, and autoimmune diseases.
The detection of identified proteins by electron microscopy, which makes use of specific antibodies that are tagged with a marker, usually colloidal gold, for visualization in the electron microscope.
LASER-SCANNING MICROSCOPY ...
acetylcholinesterase (AChE) - an enzyme that catalyzes hydrolysis of the neurotransmitter acetylcholine into acetate and choline. Expression of AChE can serve as a marker of skeletal muscle differentiation.
fibrillarin, a small nuclear ribonucleoprotein (SnRNP) involved in ribosomal RNA processing and centralized within the sub-organelle. Fibrillarin has a well conserved amino acid sequence that enables the protein to serve as an excellent marker ...
 See also: DNA, Sequence, Human, Chromosome, Gene
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