Megabase (Mb): Unit of length for DNA fragments equal to 1 million nucleotides and roughly equal to 1 cM.
Megabase cloning. The cloning of very large DNA fragments. (See Cloning.) ...
megabase
MDG
Millennium Development Goal (of the UN Millennium Project) ...
(See Directional cloning, Megabase cloning, Molecular cloning, Subcloning.) Coat protein (capsid). The coating of a protein that enclosed the nucleic acid core of a virus. Codon.
Mb megabase
MBC Massachusetts Biotechnology Council
MBL Marine Biological Laboratory
MCD Mouse Cytogenetic Database
MDA Muscular Dystrophy Assoc.
MEMS Microelectromechanical Systems
MGC Mouse Genome Conference ...
The latter platform sequences roughly 100 megabases in a 7-hour run with a single machine. In the array-based method (commercialized by 454 Life Sciences), single-stranded DNA is annealed to beads and amplified via emPCR.
As a very rough rule of thumb, we shall assume that 1 cM on a chromosome encompasses 1 megabase (1 Mb = 106 bp) of DNA. But for the reasons mentioned above, this relationship is only approximate.
In the 24 April 2003 issue of Nature, the genome of N. crassa was reported as completely sequenced. The genome is about 43 megabases long and includes approximately 10,000 genes.
Agarose gels: A polysaccharide gel used to measure the size of nucleic acids (in bases or base pairs). See "Gel Electrophoresis". This is the gel of choice for DNA or RNA in the range of thousands of bases in length, or even up to 1 megabase if you ...
 See also: Genome, Sequence, Human, Sequencing, Mapping
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