Minisatellite A DNA sequence of about 20 to 50 nucleotides which are tandemly repeated from about 5 to 100 times. A locus containing a minisatellite is often polymorphic because of variation in the repeat number.
Minisatellite
Highly polymorphic DNA markers comprised of a variable number of tandem repeats that tend to cluster near the telomeric ends of chromosomes. The repeats often contain a repeat of 10 nucleotides. They are used for genetic mapping. Cf.
Minisatellite: Short repeats of nucleotides.
Microsatellite: Very short repeats of nucleotides. Some trinucleotide repeats are found in coding regions (see, Trinucleotide repeat disorder). Most are found in noncoding regions.
See also: minisatellite, mobile element , transposon, short interspersed repetitive element , long interspersed repetitive element , junk DNA, selfish DNA
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Directed amplification of minisatellite region DNA (DAMD)
A technique for detecting polymorphisms using VNTR core sequences as primers for PCR.
Related Terms:
Polymorphism
Difference in DNA sequence among individuals.
Pena (Universidade Federal de Minas Gerais, Brazil) presented data on a minisatellite DNA. He isolated a probe from the parasite Schistosoma mansoni, which has many of the consensus sequences present in Jeffreys' human VNTR (i.e.
 See also: DNA, Sequence, Microsatellite, Marker, Gene
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