Missense Mutation
A missense mutation is when the change of a single base pair causes the substitution of a different amino acid in the resulting protein. This amino acid substitution may have no effect, or it may render the protein nonfunctional.
Missense mutations
With a missense mutation, the new nucleotide alters the codon so as to produce an altered amino acid in the protein product.
Missense mutation
A mutation that changes a codon for one amino acid to a codon for a different amino acid, resulting in an amino acid substitution in the protein product.
missense mutation
The most common type of mutation involving a base-pair substitution within a gene that changes a codon, but the new codon makes sense in that it still codes for an amino acid.
mitochondrial matrix ...
Missense mutations or nonsynonymous mutations are types of point mutations where a single nucleotide is changed to cause substitution of a different amino acid. This in turn can render the resulting protein nonfunctional.
Missense mutation A mutation which changes the amino acid incorporated into the coded polypeptide chain.
Mitochondrial DNA The DNA of the mitochondrial genome.
p53 Mutation Database The p53 mutation database contains information on all p53 missense mutations and small deletions in human tumors and cell lines as reported in peer-reviewed literature.
Three kinds of point mutations can occur. A mutation that results in an amino acid substitution is called a missense mutation.
A mutation that results in a stop codon so that incomplete proteins are produced, it is called a nonsense mutation.
Missense mutation -- a change in the base sequence of a gene that alters or eliminates a protein. Mitochondrial DNA -- the mitochondrial genome consists of a circular DNA duplex, with 5 to 10 copies per organelle.
 See also: Sense, Trans, Mutation, Gene, Protein
  
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