Mitotic recombination. The study of tumor suppressor genes revealed (for the first time) that crossing over — with genetic recombination — occasionally occurs in mitosis (as it always does in meiosis).
Therefore the minimal length of a unique sequence required for gene isolation is only 2 times larger than the minimal size of homology required for spontaneous mitotic recombination in yeast.
 See also: Human, Trans, Order, Mouse, Recombination
  
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