[edit] Mosaicism
Trisomy 21 is caused prior to conception, and all cells in the body are affected. However, when some of the cells in the body are normal and other cells have trisomy 21, it is called Mosaic Down syndrome (46,XX/47,XX,+21).
Mosaicism
Condition in which an individual harbors 2 or more genetically distinct cell lines; results from a genetic change after formation of a zygote, ie postzygotic event. Cf. germ line mosaicism.
Related Terms:
Zygote ...
Mosaicism for aneuploid chromosome content may be part of the constitutional ... Aneuploid neurons are functionally active and integrated into brain circuitry" ...
Full article ...
Germline mosaicism Two populations of cells making up the germline of one individual. Caused by mutation and proliferation of one cell out of the population of germline cells.
Example of Mosaicism: Calico Cats
A calico cat has patches of orange and patches of black
X = orange ...
Down syndrome -- a type of mental deficiency due to trisomy (three copies) of autosome 21, a translocation of 21 or mosaicism.
Non-traditional inheritance: mosaicism, microdeletion syndromes, uniparental disomy, genomic imprinting, trinucleotide repeats, mitochondrial disorders
The events in sexual development and some genetic abnormalities ...
This causes a pattern of gene expression called mosaicism, which occurs when different alleles of X-linked genes are expressed in different cells.
Mosaicism Where a genetic or chromosomal abnormality does not occur in all body cells. Often related to X chromosome innactivation.
mRNA See messenger RNA.
Multifactorial or multigenic disorders See polygenic disorders.
 See also: Trans, Chromosome, Cells, Human, Chromosomes
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