Mutational meltdown refers to the process by which a small population accumulates deleterious mutations, which leads to loss of fitness and decline of the population size, which leads to further accumulation of deleterious mutations.
mutation rate
the rate at which mutations occur at a specific locus; usually expressed as mutations per gamete per locus per generation
Source: Jenkins, John B. 1990. Human Genetics, 2nd Edition. New York: Harper & Row ...
Mutations
In the living cell, DNA undergoes frequent chemical change, especially when it is being replicated (in S phase of the eukaryotic cell cycle). Most of these changes are quickly repaired. Those that are not result in a mutation.
Mutations are changes in the DNA sequence of a cell's genome and are caused by radiation, viruses, transposons and mutagenic chemicals, as well as errors that occur during meiosis or DNA replication.
Search for mutation in these other databases too
Definition of mutation :
1) The process producing a gene or a chromosome differing from the wild-type.
2) The gene or chromosome that results from such a process.
The number of mutation events per gene per unit of time (for example, per cell generation). The proportion of mutations per cell division in bacteria or single-celled organisms or the proportion of mutations per gamete in higher organisms.
Mutation
A mutation is a change in a DNA sequence. Mutations can result from DNA copying mistakes made during cell division, exposure to ionizing radiation, exposure to chemicals called mutagens, or infection by viruses.
Mutation Studies by Joe Boxhorn
The material in this section is by Joe Boxhorn. It goes into greater depth than the material in the rest of the FAQ. It gives a good picture of how experiments are actually run.
Chapter 11
Mutations of the mitochondrial genome:clinical overview and possible pathophysiology of cell damage
Steven M.Rothman ...
Mutation Research Journal Adds New Section
In 1997 Mutation Research will devote a new section to the union between genomics and mutation research.
Mutation
Mutations are random occurrences which change the genome of an organism. They greatly increase genetic diversity, where advantageous mutations are favoured by natural selection and disadvantageous ones are phased out.
Gene Migration ...
Mutations: Somatic and Germinal, Single Gene and Chromosomal
P 68-73, 76-7, 316-35
T Ch 9, 16
Gene mutations, cancer, gonadal mosaicism and sporadics, polymorphisms, allelic and locus heterogeneity, VNTRs, STRs ...
Mutation
Any heritable alteration in the base sequence of the genetic material. See Types of mutations ...
Mutation: A spontaneous or induced change in the DNA of a cell.
Nucleotide: A molecular subunit of DNA or RNA consisti ng of a base (adenine, guanine, thymine, or cytosine in DNA; adenine, guanine, uracil, or cytosine in RNA).
Mutation: Any inheritable change in DNA sequence.
Mutation breeding: Commonly used practices in plant breeding and other areas in which chemicals or radiation are applied to whole organisms, for example plants, ...
Mutation (myoo-TAY-shun) A change in a DNA sequence.
Myelin (MY-eh-lin) A fatty covering that forms a protective sheath around nerve fibers and dramatically speeds the transmission of nerve signals.
mutation
(myoo-tay-shun) [L. mutare, to change]
A rare change in the DNA of genes that ultimately creates genetic diversity.
mutualism ...
mutation Any heritable change in the nucleotide sequence of DNA; can involve substitutions, insertions, or deletions of one or more nucleotides.
mutation rate The average occurrence of mutations in a species per a given unit of time.
mutation. The abrupt appearance of a new, heritable characteristic as the result of a change in the genetic material of one individual cell.
Mutation A change in DNA sequence from one generation (or cell generation) to the next.
Mutation Rate The frequency with which mutations occur.
Mutation. An alteration in DNA structure or sequence of a gene. (See Point mutation.)
Mutualism. See Symbiosis.
Mycorrhizae. Fungi that form symbiotic relationships with roots of more developed plants.
Mutation a change in a gene
(muta = change)
Myocardial Infarction death of a portion of the heart muscle due to lack of blood supply due to a blocked artery
(myo = muscle; cardio = heart; infarct = filled in‚ stuffed) ...
Mutation
A permanent structural alteration in DNA. In most cases, DNA changes either have no effect or cause harm, but occasionally a mutation can improve an organism's chance of surviving and passing the beneficial change on to its descendants.
Mutations Variations that alter the meaning of the genetic message; required for evolution.
A mutation is a change in the genetic instructions (DNA) of an individual.
The change is usually harmful but occasionally it is beneficial.
Dynamic mutation: Changes in the DNA-repeat copy number of an STR locus. Such changes are responsible for diseases like fragile X syndrome, myotonic dystrophy and Huntington disease as well as genetic anticipation.
Mutation
The term which De Vries introduced into biological literature for an abrupt change of genotype which is inherited. Any permanent and heritable change in DNA sequence.
Mutations in the antigenic structure of the influenza virus have resulted in a number of different influenza subtypes and strains.
Mutations enable HIV to avoid treatments that involve only one drug, so there is growing use of multiple-drug therapies in which both a protease inhibitor AND a reverse transcript inhibitor are combined.
Return to Overview of HIV Infection.
Mutations
- Changes in the gene which are heritable and essentially permanent
Mutator gene ...
Mutations in p53 are almost all cell specific-occasionally they are inherited. But mostly they are mutations that either abrogate the function of p53 entirely or alter its function.
mutation - a change in the DNA sequence that constitutes a genetic mistake.
oligosaccharides. Polysaccharides are molecules with thousands of monosaccharideunits.
mutation pressure The constant resupplying of mutations to a gene pool due to a base mutation rate.
No mutation: no allelic changes occur.
No gene flow: migration of alleles into or out of the population does not occur.
Random mating: individuals pair by chance and not according to their genotypes or phenotypes.
BACK MUTATION - Reverse the effect of a point or frame-shift mutation that had altered a gene; thus it restores the wild-type phenotype (see REVERTANT).
Point mutation
A change in a single base pair of DNA.
Related Terms:
Base pair (bp) ...
Assume that a mutation occurs in protein 2 that changes the amino acid shown above to one of the amino acids shown below.
What change should disrupt the interaction between proteins 1 and 2 the most? the least?
Insertional mutation See: insertion
Interference One crossover event inhibits the chances of another crossover event. Also known as positive interference. Negative interference increases the chance of a second crossover.
spontaneous Mutations that occur in the absence of treatment with a chemical or biological mutagen. Usually refers to mutations in natural populations.
insertion
A mutation involving the addition of one or more nucleotide pairs to a gene.
insertion
The more movable attachment point of a muscle.
Usually refers to diseases that are inherited in a Mendelian fashion, although noninherited forms of cancer also result from DNA mutation. Genetic drift. Random variation in gene frequency from one generation to another. Genetic engineering.
Allele -- an alternative form of a gene; any one of several mutational forms of a gene. Alpha-fetoprotein (AFP) -- a protein excreted by the fetus into the amniotic fluid and from there into the mother's bloodstream through the placenta.
Auxotrophic mutantA bacterial strain which has a mutation in at least one of the enzymes in a biochemical pathway responsible for synthesising an essential substance, for example an amino acid.
Mutant A gene having undergone genetic change or mutation.
Mutation Any heritable change in DNA sequence. Compare polymorphism.
Nucleic acid A large molecule composed of nucleotide subunits.
Oncology - the study of cancer processes, including virus or mutation oncogenesis, angiogenesis and tissues remoldings
Ornithology - the study of birds ...
 See also: Organ, Trans, DNA, Human, Gene
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