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Nuclein

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Later nuclein was resolved into an acidic component, nucleic acid,and a basic component, primarily proteins known as histones.
Eukaryotic cells contain a distinct structure, the nucleus, where nuclein was localized.


Honore B, Baandrup U, Nielsen S, Vorum H: Endonuclein is a cell cycle regulated WD-repeat protein that is up-regulated in adenocarcinoma of the pancreas.
Andersen JS, Lyon CE, Fox AH, Leung AK, Lam YW, Steen H, Mann M, Lamond AI: Directed proteomic analysis of the human nucleolus. ...

He called the compound nuclein. This is today called nucleic acid, the NA in DNA (deoxyribo-nucleic-acid) and RNA (ribo-nucleic-acid).
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Nucleic acids were discovered in 1868 by Friedrich Miescher, who called the material 'nuclein' since it was found in the nucleus.[44] It was later discovered that prokaryotic cells, which do not have a nucleus, also contain nucleic acids.

In that timeline "biochmists" in the early 1900's are credited with the discovery that "nuclein" (DNA) is made up of nucleotides which contain a phosphate group, a 5-carbon sugar, and a nitrogen base. Who were these scientists?

Since it came from nuclei, Meischer named this new chemical, nuclein. Subsequently the name was changed to nucleic acid and lastly to deoxyribonucleic acid (DNA). Robert Feulgen, in 1914, discovered that fuchsin dye stained DNA. DNA was then found in the nucleus of all eukaryotic cells.

~. The term used by Friedrich Miescher to describe the nuclear material he discovered in 1869, which today is known as DNA. Nucleoside. A building block of DNA and RNA, consisting of a nitrogenous base linked to a five carbon sugar. (See Nucleoside analog.) Nucleoside analog.

See also: See also: What is the meaning of Protein, Cells, Proteins, Trans, Sequence?

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